期刊文献+

Role of color Doppler in differentiation of Graves' disease and thyroiditis in thyrotoxicosis 被引量:4

Role of color Doppler in differentiation of Graves' disease and thyroiditis in thyrotoxicosis
在线阅读 下载PDF
导出
摘要 AIM:To evaluate the role of thyroid blood flow assessment by color-flow Doppler ultrasonography in the differential diagnosis of thyrotoxicosis and compare it to technetium pertechnetate thyroid scanning. METHODS:Twenty-six patients with thyrotoxicosis were included in the study. Clinical history was taken and physical examination and thyroid function tests were performed for all patients. Thyroid autoantibodies were measured. The thyroid glands of all patients were evaluated by gray scale ultrasonography for size, shape and echotexture. Color-flow Doppler ultrasonography of the thyroid tissue was performed and spectral flow analysis of both inferior thyroid arteries was assessed. Technetium99 pertechnetate scanning of the thyroid gland was done for all patients. According to thyroid scintigraphy, the patients were divided into two groups:18 cases with Graves' disease and 8 cases with Hashimoto's thyroiditis. All patients had suppressed thyrotropin. The diagnosis of Graves' disease and Hashimoto's thyroiditis was supported by the clinical picture and follow up of patients. RESULTS:Peak systolic velocities of the inferior thyroid arteries were significantly higher in patients with Graves' disease than in patients with thyroiditis (P = 0.004 in the right inferior thyroid artery and P = 0.001 in left inferior thyroid artery). Color-flow Doppler ultrasonography parameters demonstrated a sensitivity of 88.9% and a specificity of 87.5% in the differential diagnosis of thyrotoxicosis. CONCLUSION:Color Doppler flow of the inferior thyroid artery can be used in the differential diagnosis of thyrotoxicosis, especially when there is a contraindication of thyroid scintigraphy by radioactive material in some patients. AIM:To evaluate the role of thyroid blood flow assessment by color-flow Doppler ultrasonography in the differential diagnosis of thyrotoxicosis and compare it to technetium pertechnetate thyroid scanning. METHODS:Twenty-six patients with thyrotoxicosis were included in the study. Clinical history was taken and physical examination and thyroid function tests were performed for all patients. Thyroid autoantibodies were measured. The thyroid glands of all patients were evaluated by gray scale ultrasonography for size, shape and echotexture. Color-flow Doppler ultrasonography of the thyroid tissue was performed and spectral flow analysis of both inferior thyroid arteries was assessed. Technetium99 pertechnetate scanning of the thyroid gland was done for all patients. According to thyroid scintigraphy, the patients were divided into two groups:18 cases with Graves’ disease and 8 cases with Hashimoto’s thyroiditis. All patients had suppressed thyrotropin. The diagnosis of Graves’ disease and Hashimoto’s thyroiditis was supported by the clinical picture and follow up of patients. RESULTS:Peak systolic velocities of the inferior thyroid arteries were significantly higher in patients with Graves’ disease than in patients with thyroiditis (P = 0.004 in the right inferior thyroid artery and P = 0.001 in left inferior thyroid artery). Color-flow Doppler ultrasonography parameters demonstrated a sensitivity of 88.9% and a specificity of 87.5% in the differential diagnosis of thyrotoxicosis. CONCLUSION:Color Doppler flow of the inferior thyroid artery can be used in the differential diagnosis of thyrotoxicosis, especially when there is a contraindication of thyroid scintigraphy by radioactive material in some patients.
出处 《World Journal of Radiology》 CAS 2013年第4期178-183,共6页 世界放射学杂志(英文版)(电子版)
关键词 DOPPLER THYROTOXICOSIS THYROID SCINTIGRAPHY Graves’ diseases THYROIDITIS Doppler Thyrotoxicosis Thyroid scintigraphy Graves’ diseases Thyroiditis
  • 相关文献

参考文献34

  • 1Bogazzi F,Bartalena L,Brogioni S,et al.Thyroid vascularity and blood flow are not dependent on serum thyroid hormone levels: studies in vivo by color flow Doppler sonography. European Journal of Endocrinology . 1999
  • 2Ralls PW,Magekawa Ds,Lee KP,et al.Color-flow doppler sonography in graves disease:" thyroid inferno". American Journal of Roentgenology . 1988
  • 3C.Cappelli,I.Pirola,E.De Martino,et al.The role of imaging in Graves‘ disease:A cost-effectiveness analysis. E J R . 2008
  • 4Vitti P,Rago T,Mazzeo S,et al.Thyroid blood flow evaluation by color-flow Doppler sonography distinguishes graves’ disease from Hashimotos’ thyroiditis. Journal of Endocrinological Investigation . 1995
  • 5Sponza M,Fabris B,Bertolotto M,et al.Role of Doppler color ultrasonography and of flowmetric analysis in the diagnosis and follow-up of Grave ’ s disease. Radiologia Medica . 1997
  • 6Gharib,H,Papini,E,Valcalvi,R,Baskin,H.J,Crescenzi,A,Dottorini,M.E,Duick,D.S,Guglielmi,R,Hamilton,C.R.Jr,Zeiger,M.A.et al.American Associationof Clinical Endocrinologists and Associazione MediciEndocrinologi medical guidelines for clinical practice forthe diagnosis and management of thyroid nodules. En-docr. Pract . 2006
  • 7Cappelli C,Castellano M,Pirola I,Cumetti D,Agosti B,Gandossi E,et al.The predictive value of ultrasoundfindings in the management of thyroid nodules. Quarterly Journal of Mathematics . 2007
  • 8Wang CY,Chang TC.Thyroid Doppler ultrasonography and resistiveindexinthe evaluation of the needfor ablativeor antithyroid drug therapy in Graves’hyperthyroidism. Journal of the Formosan Medical Association . 2001
  • 9Nagasaki T,Inaba M,Kumeda Y,et al.Significance of thyroid blood flow as a predictor of methimazole sensitivity in untreated hyperthyroid patients with Graves’’ disease. Biomedicine and Pharmacotherapy . 2007
  • 10Markovic V,,Eterovic D.Thyroid echogenicity predicts outcomeof radioiodine therapy in patients with Graves’’disease. Journal of Clinical Endocrinology and Metabolism . 2007

同被引文献9

引证文献4

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部