摘要
目的对左氧氟沙星2种给药方案治疗泌尿生殖系统感染进行药物经济学评价。方法将83例泌尿生殖系统感染患者随机分为A、B组,其中A组44例采用左氧氟沙星注射液连续静脉滴注,B组39例采用左氧氟沙星注射液/胶囊序贯给药,并对2种方案进行药物经济学分析。结果两组在有效率、细菌清除率及不良反应发生率方面差异无统计学意义(P>0.05),但A组的治疗成本却明显高于B组(P<0.05)。结论左氧氟沙星序贯给药治疗泌尿生殖系统感染方案较佳。
Objective To evaluate the pharmacoeconomic outcome of 2 therapeutic schemes of levofloxacin in treatment of genitourinary infections.Methods 83 patients with genitourinary infections were randomly divided into group A and group B.44 cases in group A were assigned to receive levofloxacin injection by continuous intravenous drip,another 39 cases in group B to receive levofloxacin injection/capsule by sequential therapy.The pharmacoeconomic analysis was performed on the 2 groups.Results No significant difference noted between 2 groups in effective rates,bacterial clearance rates,and incidences of ADRS(P>0.05),but the treatment cost in group A was significantly higher than in group B(P<0.05).Conclusion The sequential therapy with levofloxacin for genitourinary infections is preferable.
出处
《中国现代药物应用》
2007年第5期15-16,共2页
Chinese Journal of Modern Drug Application
关键词
左氧氟沙星
序贯给药
药物经济学
Levofloxacin
Sequential therapy
Pharmacoeconomics
