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广州汉族群体DYS391基因座多态性分析 被引量：1

A study on polymorphism of the DYS391 locus of Han population in Guangzhou of Guangdong province
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摘要 目的探讨Y—STR基因座DYS391的多态性及其法医学应用价值。方法用荧光标记引物、变性PAGE、激光自动扫描检测PCR扩增产物的方法,调查广州地区111例汉族无关男性个体DYS391等位基因分布状况;对该位点的种属特异性、突变率及其在混合斑个体识别中的价值等与法医学应用有关的问题进行了研究。结果DYS391基因座共检出3个等位基因,人类特异性较高,未发现突变。结论Y—SIR基因座DYS391的基因检测在法医物证学中的应用价值大,尤其是在父权鉴定及混合斑的个体识别中具有其它方法不具备的优越性。 Objective To evaluate the polymorphism and forensic applicability of Y - DNA STR locus DYS391. Method 111 unrelated male samples from Guangzhou Han population were investigated.DYS391 primer was labeled with FAM. PCR products were detected using denatured PAGE with GenScan Software on the ABI Prism 377 DNA sequencer.Results Frequency data of 3 different DYS391 alleles were obtained. Conclusion The results demonstrated that the DYS391 locus is of high human specificity. No mutation was found.
作者 李越 王穗保 刘超 唐双柏 李红霞 郭景元
机构地区 广州市刑事科学技术研究所 中山大学中山医学院法医学系
出处 《中国法医学杂志》 CSCD 2002年第S1期20-21,共2页 Chinese Journal of Forensic Medicine
关键词 法科学 DYS391基因座 遗传多态现象 个体识别 Forensic science DYS391 locus Genetic polymorphism Personal identification
分类号 D919 [医药卫生—法医学]
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参考文献9

  • 1唐双柏,郭景元,刘超,梁赏猷,王穗保.广州地区汉族人群Y染色体多个STR位点的研究[J].法医学杂志,1999,15(2):86-88. 被引量：14
  • 2郑秀芬,王小娅.Y-染色体及其在法医鉴定中的作用[J].中国法医学杂志,1998,13(3):183-187. 被引量：8
  • 3P. de Knijff,M. Kayser,A. Caglià,D. Corach,N. Fretwell,C. Gehrig,G. Graziosi,F. Heidorn,S. Herrmann,B. Herzog,M. Hidding,K. Honda,M. Jobling,M. Krawczak,K. Leim,S. Meuser,E. Meyer,W. Oesterreich,A. Pandya,W. Parson,G. Penacino,A. Perez-Lezaun,A. Piccinini,M. Prinz,C. Schmitt,P. M. Schneider,R. Szibor,J. Teifel-Greding,G. Weichhold,L. Roewer.Chromosome Y microsatellites: population genetic and evolutionary aspects[J]. International Journal of Legal Medicine . 1997 (3)
  • 4M. Kayser,A. Caglià,D. Corach,N. Fretwell,C. Gehrig,G. Graziosi,F. Heidorn,S. Herrmann,B. Herzog,M. Hidding,K. Honda,M. Jobling,M. Krawczak,K. Leim,S. Meuser,E. Meyer,W. Oesterreich,A. Pandya,W. Parson,G. Penacino,A. Perez-Lezaun,A. Piccinini,M. Prinz,C. Schmitt,P. M. Schneider,R. Szibor,J. Teifel-Greding,G. Weichhold,P. de Knijff,L. Roewer.Evaluation of Y-chromosomal STRs: a multicenter study[J]. International Journal of Legal Medicine . 1997 (3)
  • 5Nei M.Analysis of gene diversity in subdivided populations. Proceedings of the National Academy of Sciences of the United States of America . 1973
  • 6Walsh PS,Metzger DA,higuchi R.Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques . 1991
  • 7Gusmao L,Gonzalez-Neira A,Sanchez-Diz P,et al.Alternative primers for DYS391 typing : advantages of their application to forensic genetic. Forensic Science International . 2000
  • 8Prinz M,Boll K,Baum H,et al.Multiplexing of Y chromosome specific STRs and performance for mixed samples. Forensic Science International . 1997
  • 9Holland MM,Fisher DL,Mitchell LG,et al.Mitochondrial DNA sequence analysis of human skeletal remains: identification of remains from the Vietnam War. Journal of Forensic Sciences . 1993

二级参考文献6

  • 1金冬雁 黎孟枫（等）.分子克隆实验指南（第二版）[M].北京:科学出版社,1992.60-69.
  • 2M. Kayser,A. Caglià,D. Corach,N. Fretwell,C. Gehrig,G. Graziosi,F. Heidorn,S. Herrmann,B. Herzog,M. Hidding,K. Honda,M. Jobling,M. Krawczak,K. Leim,S. Meuser,E. Meyer,W. Oesterreich,A. Pandya,W. Parson,G. Penacino,A. Perez-Lezaun,A. Piccinini,M. Prinz,C. Schmitt,P. M. Schneider,R. Szibor,J. Teifel-Greding,G. Weichhold,P. de Knijff,L. Roewer. Evaluation of Y-chromosomal STRs: a multicenter study[J] 1997,International Journal of Legal Medicine(3):125～133
  • 3Fabrício R. Santos,Tudevdagva Gerelsaikhan,Bjamba Munkhtuja,Tsendsuren Oyunsuren,J?rg T. Epplen,Sérgio D. J. Pena. Geographic differences in the allele frequencies of the human Y-linked tetranucleotide polymorphism DYS19[J] 1996,Human Genetics(3):309～313
  • 4. DNA recommendations —1994 report concerning further recommendations of the DNA Commission of the ISM regarding PCR-based polymorphisms in STR (short tandem repeat) systems[J] 1994,International Journal of Legal Medicine(3):159～160
  • 5Sibylle Jakubiczka,Joachim Arnemann,Howard J. Cooke,Michael Krawczak,J?rg Schmidtke. A search for restriction fragment length polymorphism on the human Y chromosome[J] 1989,Human Genetics(1):86～88
  • 6张勇,张贵寅,孙艳阳,薛雅丽,杨焕杰,陈白滨,李璞.中国东北汉族及3个少数民族DYS19和DYS287多态性研究[J].人类学学报,1998,17(3):237-241. 被引量：8

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中国法医学杂志
2002年 第S1期

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