摘要
目的 观察PSP对S180肉瘤小鼠T淋巴细胞亚群及肿瘤细胞凋亡的影响 ,并探讨其免疫调节及抗肿瘤的作用机制。方法 FACSCalibur流式细胞仪检测荷瘤鼠T淋巴细胞亚群及肿瘤细胞凋亡。结果 PSP能调节CD4 + /CD8+ 细胞的比例 ,诱导肿瘤细胞凋亡。结论 PSP可改善机体异常的免疫状态 ,调节免疫系统的失衡 。
Objective To investigate the effect of PSP on subset of T cell and apoptosis of tumor cell from S180 cells mice and to study PSP the function of immunoregulation and the mechanism of antitumor.Methods The subset of T cell and apoptosis of tumor cell was detected by flow cytometer.Results That PSP could regulate the ratio of CD4 +/CD8 + cell, provoked the apoptosis of tumor cell. Conclusions PSP can improve abnormal state of immune, regulate the imbalance of immune function and promote the tumor cells’ apoptosis.
出处
《齐齐哈尔医学院学报》
2004年第5期485-487,共3页
Journal of Qiqihar Medical University
基金
黑龙江省科委自然科学基金资助课题 (D0 0 - 1 7)一部分内容
关键词
桃仁总蛋白
荷瘤鼠
T淋巴细胞亚群
细胞凋亡
免疫调节
动物模型
中药
Activating blood flow and removing blood stasis P.Persica (linn) batch seeds protein Immunoregulation Apoptosis
