摘要
目的分析先天畸形在徐州市普通人群中的流行病学特点。方法采用分层整群随机抽样的调查方法。结果调查９８６４２人，发现先天畸形６６种，患者５４９人，患病率为５．５４％。患者中男性明显多于女性，１０岁以下的儿童占患者总数的４９．８％。多基因病、单基因病和染色体病的患病率分别为２．８７‰、１．９１‰和０．１０‰。排在前３位的病种是腹股沟斜疝、先天性心脏病、先天性聋哑。结论徐州市普通人群中先天畸形病种多，一些严重畸形发病率高。应采取监控措施，减少出生缺陷的发生。
Objective To study the epidemiologic characteristics of congenital malformation in the normal population of Xuzhou,Jiangsu.Methods Stratified chester random sampling.Results A total of 549 cases and 66 forms of congenital malformation were found in 98642 residents in this area.The total prevalence rate was 5.54‰.There was a significant higher prevalence in male patients than in female.49.8% of patients were children under 10 years old.The prevalence of polygenic diseases,monogenic diseases and chromosomal diseases was 2.87‰,1.91‰ and 0.10‰ respectively.The first three of the congenital malformations defected were inguinal oblique hernia,congenital heart diseases and congenital deaf and mutism.Conclusion The variety of congenital malformation and the high prevalence of certain serious malformations in the city of Xuzhou indicate the necessity of monitoring to minimize the number of neonates with defects.
出处
《徐州医学院学报》
CAS
1997年第6期23-26,共4页
Acta Academiae Medicinae Xuzhou
基金
江苏省卫生厅妇幼处资助
关键词
先天性畸形
遗传流行病学
Congenital malformation Genetic epidemiology
