摘要
目的评价对比半导体二极管激光经巩膜睫状体光凝术(transscleral cylophotocoagulation,TSCPC)和睫状体冷凝术治疗晚期新生血管性青光眼(neovascular glaucoma,NVG)的临床疗效。方法选取2011年1月至2012年12月就诊于我院的晚期NVG患者60例(60眼),按照手术方式的不同分为TSCPC组(32例,32眼)和睫状体冷凝术组(28例,28眼)。比较术后两组患者的治疗效果、眼球疼痛缓解率、眼压及并发症。结果 TSCPC组治疗有效率为84.4%(27/32),睫状体冷凝术组为78.6%(22/28),差异无统计学意义(χ2=0.438,P=0.601)。TSCPC组眼球疼痛缓解率为93.8%(30/32),睫状体冷凝术组为85.7%(24/28),差异无统计学意义(χ2=0.248,P=1.333)。两组患者手术前后眼压差异均有显著统计学意义(t=12.736、10.898,均为P=0.000),2组间术后眼压差异有显著统计学意义(t=12.423,P=0.000),TSCPC组低于睫状体冷凝术组。两组均不同程度发生角膜水肿、前房纤维素渗出、前房出血、晶状体混浊加重等并发症,其中TSCPC组前房纤维素渗出和角膜水肿的发生率显著低于睫状体冷凝术组,差异均有统计学意义(均为P<0.05)。结论与睫状体冷凝术相比,TSCPC是治疗晚期NVG更安全有效的方法。
Objective To evaluate the clinical effects of transscleral cylophotocoagulation(TSCPC)and cyclocryo surgery for later neovascular glaucoma(NVG),Methods A total of 60 cases(60 eyes)with later NVG in our hospital from January 2011 to December 2012 were randomly divided into TSCPC group(32 cases,32 eyes)and cyclocryosurgery group(28 cases,28 eyes)according to different surgical methods.The therapeutic effect,eye pain remission rate,intraocular pressure and postoperative complications were observed before and after operation. Results After operation,the therapeutic effect and eye pain remission rate in TSCPC group were 84.4%(27/32)and 93.8%(30/32),respectively Which in cyclocryosurgery group were 78.6%(22/28)and 85.7%(24/28),respectively, there was no statistical difference between two groups(X^2=0.438,0.248;P=0. 601,1.333).There were statistical differences in intraocular pressure of two groups between pre-operation and post-operation(t=12.736,10.898;both P=0.000), significant difference in postoperative intraocular lens between two groups(t=12. 423,P=0.000).The corneal edema,anterior chamber fibrin exudation,hyphema and grave lens opacity after operation appeared in two groups,but only in anterior chamber fibrin exudation and corneal edema there were statistical differences between two groups(all P<0.05),the TSCPC group was significant lower than cyclocryosurgery group.Conclusion Compared with cyclocryo surgery,TSCPC is a more safe and effective method for late NVG.
出处
《眼科新进展》
CAS
北大核心
2013年第12期1150-1152,共3页
Recent Advances in Ophthalmology
