摘要
目的：分析2型糖尿病伴发单发性和多发性腔隙性脑梗死的危险因素。方法将2009年6月至2012年6月潮州医院收治的185例2型糖尿病患者分为3组，A组为单纯2型糖尿病（104例），B 组为2型糖尿病伴发单发性腔隙性脑梗死（59例），C 组为2型糖尿病伴发多发性腔隙性脑梗死（22例）。对2型糖尿病伴发单发性和多发性腔隙性脑梗死的危险因素进行分析。结果多因素 Logistic 回归分析结果显示，颈动脉内膜厚度（CIMT）、尿微量白蛋白（MA）、C-反应蛋白（CRP）、糖化血红蛋白（HbA1c）、甘油三酯（TG）、重度颈动脉狭窄以及高血压病史是2型糖尿病伴发单发性腔隙性脑梗死的独立危险因素（P<0.05）。血清总胆固醇（TC）、CIMT、MA、CRP、HbA1c、TG、高密度脂蛋白（HDL-C）、低密度脂蛋白（LDL-C）、重度颈动脉狭窄及高血压病史是2型糖尿病伴发多发性腔隙性脑梗死的独立危险因素（P<0.05）。结论2型糖尿病患者伴发单发性和多发性腔隙性脑梗死的发生危险因素不太一致，应根据各自的危险因素进行防控。
Objective To investigate the risk factors of type-2 diabetes combined with lacunar cerebral infarction. Methods 185 cases of type 2 diabetic patients were divided into 3 groups.Group A,type-2 diabetes without combined with lacunar cerebral infarction(104 cases);group B,type 2 diabetes combined with single lacunar cerebra infarction(59 cases);group C,type 2 diabetes combined with multiple lacunar cerebral infarction(22 cases).In type 2 diabetes mellitus with factors of single and multiple lacunar cerebral infarction were analyzed. Results Multivariate Logistic regression analysis showed, CIMT, MA, CRP, HbA1c, TG, severe carotid stenosis and hypertension history were the independent risk factors of lacunar cerebral infarction with single piece of type 2 diabetes mellitus (P<0.05). TC, CIMT, MA, CRP, HbA1c, TG, HDL-C, HDL-C, severe carotid stenosis and hypertension history were the independent risk factors for multiple lacunar cerebral infarction in type 2 diabetes patients with one (P<0.05). Conclusion The risk factors affect the type 2 diabetes combined with single lacunar cerebral infarction and type 2 diabetes combined with multiple lacunar cerebral infarction arc different,which needs to make a difference in clinic.
出处
《中国临床实用医学》
2014年第3期22-24,共3页
China Clinical Practical Medicine
关键词
2
型糖尿病
腔隙性脑梗死
危险因素
分析
Type-2 diabetes
Lacunar cerebral infarction
Risk factors
Analysis
