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SDF-1/CXCR4轴与肿瘤 被引量：2

SDF-1/CXCR4 axis and tumor
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摘要 一、概述 趋化因子是一类小分子分泌型(8-14KDa)蛋白,是目前已知的最大的细胞因子家族,已发现超过50种.多数趋化因子氨基端(N端)有4个特征性的保守的半胱氨酸(Cys),相互形成二硫键.
作者 戴伟钢 董文广 王天宝
机构地区 中山大学附属第一医院胃肠胰外科
出处 《消化肿瘤杂志（电子版）》 2010年第2期115-118,共4页 Journal of Digestive Oncology(Electronic Version)
关键词 CXCR 肿瘤细胞 肿瘤干细胞 乳腺癌 乳腺肿瘤 SDF-1/CXCR4
分类号 R730.2 [医药卫生—肿瘤]
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参考文献29

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同被引文献44

  • 1Tsuboi K, Kodera Y, Nakanishi H, Ito S, Mochizuki Y, Nakayama G, Koike M, Fujiwara M, Yamamura Y, Nakao A. Expression of CXCL12 and CXCR4 in pT3-stage gastric cancer does not correlate with peritoneal metastasis. Oncol Rep 2008; 20:1117-1123 [PMID: 18949410].
  • 2Lee HJ, Kim SW, Kim HY, Li S, Yun HJ, Song KS, Kim S, Jo DY. Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer. Int J Oncol 2009; 34:473-480 [PM1D: 19148483].
  • 3陈友权,于燕妮.趋化因子SDF.1及其受体CXCR4在进展期胃癌中的表达及临床意义.长沙:中华医学会病理学分会2010年学术年会日程及论文汇编,2010.
  • 4Lee HJ, Huang SM, Kim HY, Oh YS, Hwang JY, Liang ZL, Ki Min J, Yun HJ, Sul JY, Kim S, Jo DY, Kim JM. Evaluation of the combined expression of chemokine SDF-la and its receptor CXCR4 as a prognostic marker for gastric cancer. Exp Ther Med 2011; 2:499-504 [PMID: 22977531].
  • 5Zhao BC, Zhao B, Han JG, Ma HC, Wang ZJ. Adipose-derived stem cells promote gastric cancer cell growth, migration and invasion through SDF-1/CXCR4 axis. Hepatogastroenterology 2010; 57:1382-1389 [PMID: 21443090].
  • 6Iwasa S, Yanagawa T, Fan J, Katoh R. Expression of CXCR4 and its ligand SDF-1 in intestinal-type gastric cancer is associated with lymph node and liver metastasis. Anticancer Res 2009; 29:4751-4758 [PMID: 20032431].
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引证文献2

二级引证文献4

消化肿瘤杂志（电子版）
2010年 第2期

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