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Rare adult gastric duplication cyst mimicking a gastrointestinal stromal tumor 被引量:17

Rare adult gastric duplication cyst mimicking a gastrointestinal stromal tumor
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摘要 Gastric duplication cyst is a very rare gastrointestinal tract malformation that accounts for 2%-4%of alimentary tract duplications.Most cases are diagnosed within the first year of life,following presentation of abdominal pain,vomiting,and weight loss and clinical discovery of an abdominal palpable mass.This case report describes a very uncommon symptomatic gastric duplication cyst diagnosed for the first time in adulthood.Only a few other case reports of similar condition exist,and all were identified by endosonography.The current case involves a 52-year-old male who presented with a onemonth history of progressive iron deficiency anemia without overt gastrointestinal bleeding.The patient underwent esophagogastroduodenoscopy,which revealed a 2.0 cm pinkish subepithelial lesion,suspected to be a gastrointestinal stromal tumor(GIST)and source of gastrointestinal bleeding.The endosonography showed inhomogeneous hypoechoic lesions with focal anechoic areas arising from a second and third layer of the gastric wall.Differential diagnoses of GIST,neuroendocrine tumor,or pancreatic heterotopia were made.The lesion was removed using an endoscopic submucosal resection technique.Histopathology revealed an erosive gastric mass composed of a complex structure of dilated gastric glands surrounded by fibro-muscular tissue,fibroblasts,and smooth muscle bundles,which led to the diagnosis of gastric duplication. Gastric duplication cyst is a very rare gastrointestinal tract malformation that accounts for 2%-4% of alimentary tract duplications. Most cases are diagnosed within the first year of life, following presentation of abdominal pain, vomiting, and weight loss and clinical discovery of an abdominal palpable mass. This case report describes a very uncommon symptomatic gastric duplication cyst diagnosed for the first time in adulthood. Only a few other case reports of similar condition exist, and all were identified by endosonography. The current case involves a 52-year-old male who presented with a onemonth history of progressive iron deficiency anemia without overt gastrointestinal bleeding. The patient underwent esophagogastroduodenoscopy, which revealed a 2.0 cm pinkish subepithelial lesion, suspected to be a gastrointestinal stromal tumor(GIST) and source of gastrointestinal bleeding. The endosonography showed inhomogeneous hypoechoic lesions with focal anechoic areas arising from a second and third layer of the gastric wall. Differential diagnoses of GIST, neuroendocrine tumor, or pancreatic heterotopia were made. The lesion was removed using an endoscopic submucosal resection technique. Histopathology revealed an erosive gastric mass composed of a complex structure of dilated gastric glands surrounded by fibro-muscular tissue, fibroblasts, and smooth muscle bundles, which led to the diagnosis of gastric duplication.
出处 《World Journal of Gastroenterology》 SCIE CAS 2013年第45期8445-8448,共4页 世界胃肠病学杂志(英文版)
关键词 GASTRIC DUPLICATION CYST Gastrointestinal bleeding Endoscopy ENDOSCOPIC ultrasonography ENDOSCOPIC MUCOSAL resection Differential diagnosis ADULT Gastric duplication cyst Gastrointestinal bleeding Endoscopy Endoscopic ultrasonography Endoscopic mucosal resection Differential diagnosis Adult
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参考文献6

  • 1Verena Hlouschek,Dirk Domagk,Joerg Naehrig,Joerg Ruediger Siewert,W. Domschke.Gastric duplication cyst: A rare endosonographic finding in an adult[J]. Scandinavian Journal of Gastroenterology . 2005 (9)
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  • 5Seijo Ríos S,Lari?o Noia J,Abdulkader Nallib I,Lozano León A,Vieites Pérez-Quintela B,Iglesias García J,Domínguez Mu?oz J E.[Adult gastric duplication cyst: diagnosis by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)]. Revista espa?ola de enfermedades digestivas : organo oficial de la Sociedad Espa?ola de Patología Digestiva . 2008
  • 6Napolitano Vincenzo,Pezzullo Angelo M,Zeppa Pio,Schettino Pietro,D Armiento Maria,Palazzo Antonietta,Pietra Cristina Della,Napolitano Salvatore,Conzo Giovanni.Foregut duplication of the stomach diagnosed by endoscopic ultrasound guided fine-needle aspiration cytology: case report and literature review. World journal of surgical oncology . 2013

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