摘要
目的:探讨用莫西沙星治疗耐多药性肺结核的临床效果。方法:对2011年~2012年期间我院收治的51例耐多药性肺结核患者的临床资料进行回顾性研究。我们在保证患者安全的前提下,将这51例患者随机分为实验组和对照组,其中实验组有26例患者,对照组有25例患者。我们给实验组患者使用莫西沙星进行治疗,给对照组患者使用左氧氟沙星进行治疗。两组患者的治疗时间均为18个月。治疗结果后,比较两组患者的治疗效果。结果:治疗结束后,实验组患者进行痰液菌落检查结果的转阴率为100%,对照组患者进行痰液菌落检查结果的转阴率为88%。实验组患者进行痰液菌落检查结果的转阴率明显高于对照组患者,二者相比差异具有显著性(P【0.05)。此外,实验组患者在接受治疗后,临床症状缓解的时间最短者仅为7天,最长者为23天,平均为13.2±6.8天。对照组患者在接受治疗后,临床症状缓解的时间最短者为13天,最长者为39天,平均为28±11.2天。实验组患者治疗后临床症状缓解的平均时间明显少于对照组患者,二者相比差异具有显著性(P【0.05)。结论:用莫西沙星治疗耐多药性肺结核疗效确切,可快速缓解患者的临床症状。此疗法值得在临床上推广使用。
Objective:To study the fourth generation fluorine ketone medicines Moxifloxacin in the treatment of multidrug-resistant tuberculosis infection efficacy and safety.Methods:51 pulmonary tuberculosis patients were collected in this study between 2011 to 2012 in our hospital.The cases were randomly and evenly divided into two groups.Left-handed Ofloxacin group(control group)have 25 patients and Moxifloxacin group(experimental group) have 26 patients,setting different treatment scheme,test time is 18months.Results:The results show that the experimental group sputum bacterial colonies negative rate of 100%,control group reached88%,P<0.05,but there are differences in the treatment of speed.Conclusion:Left-handed Ofloxacin and Moxifloxacin against multidrugresistant tuberculosis treatment have good curative effect,but Moxifloxacin result effect faster.
出处
《求医问药（下半月）》
2013年第10期126-127,共2页
Seek Medical and Ask The Medicine
