摘要
目的 研究尿激酶在颅内血肿微创清除术中的临床疗效。方法 5 8例高血压性脑出血经CT三维立体定位后 ,用直径 3mm的微创针穿刺血肿靶点 ,用尿激酶作生化激活溶解剂 ,每次 10 0 0 0U加生理盐水5mL注入血肿腔内 ,对血肿进行冲刷、融碎、液化、引流 ,直至血肿清除。结果 血肿清除时间 :2 4h 18例(31% ) ,2 4～ 4 8h 2 6例 (4 5 % ) ,4 8h以上 14例 (2 4 % )。全组病人无 1例术中或术后再出血 ,日常生活能力(ADL)评分明显改善。结论 尿激酶药理稳定 ,副作用少 ,使用方便 ,价格相宜 。
Objective To study the curative effect of urinekinase in hematoma removal with microsurgery. Methods 58 cases of hypertension cerebral bleeding patient were performed hematoma removal with needle under CT location and urinekinase lysis the hematoma. Results The removal time were 24 h in 18 cases, 24～48 h in 26 case and over 48 h in 14 cases. All patient had no bleeding during and after operation. ADL score was improved. Conclusion Urinekinase might be stable in pharmacology with less side effect, easy perform, cheap and accuracy effect.
出处
《黑龙江医学》
2004年第7期534-535,共2页
Heilongjiang Medical Journal
