4Brown M, Kennedy L, MacGregor A, et al. Susceptibility to ankylosing spondylitis in twins: the role of gene、 HLAand enviroment. Arthritis Rheum, 1997, 40: 1823.
2Liu Y, Li J, chen B,et al. Familial aggregation ankylosing spondylitis in Southern China[J]. J Rheumatol, 2001,28:550-553.
3Archr J, Keat A. Ankylosing spondylitis: time to focus on ankylosis[J]. J Rheumatol, 1999,26: 761-764.
4Khan M. The 21 HLA-B27 subtypes[J]. J Rheumatol,2000,27 (supp159) : 29-32.
5Lamas JR, Paradela A, Roncal F, et al. Modulation at multiple anchor positions of the peptide specifity of HLAB27 subtypes differentially associated with ankylosing spondylitis[J]. Arthritis Rheum, 1999,42:1975-1985.
6Khan M. A current perspective on ankylosing spondylitis and related spondyloarthropathies[J]. J Ind Rheum Asso,1999,7:16-21.
7Lopez-Larrea C, Gonzalez S, Martinez-Borra J, et al. The role of HLA-B27 Polymorphism and molecular mimicry in spondyloarthropathies[J]. Molecular Med Today, 1998,4:540-549.
8Ren EC, Koh WH, Sim D,et al. Possible protective role of HLA-B* 2706 for ankylosing spondylitis[J]. Tissue Antigens,1997,49:67-69.
9Fiorillo MT, Maragno M, Butler R, et al. CD8 (+) T-cell antoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis [J]. J Clin Invest, 2000,106:47-51.
10Brown M,Kennedy L, MacGregor A, et al. Susceptibility to ankylosing spondylitis in twins:the role of genes, HLA, and enviroment[J]. Arthritis Rheum, 1997,40: 1823-1828.
6Mold C,Baca R,Du Clos T W,et al.Serum amyloid P component anf C-reactive protein opsonize apoptotic cells for phagocytosisthroughFcrRs[J].JAutoimmun,2002,19:147-154.
7Mear J P,Schreiber K L.Munz C,et al.Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies[J].J Immunol,1999,163(12):6655-6670.
8Colbert R A.HLA-B27 misfolding:a solution to the spondy Ioarthropathy conundrum[J].Mol Med Today,2000,6(6):224-230,
9Banchereau J.Bazan F,Blanchard D,et al.The CD40 antigen and its ligand[J].Annu Rev Immunol,1994,12(3):881-992.
10Du Clos T W.C reactive protein as a regulator of antoimmunity and inflammation[J].Arthritis Rheum,2003,48:1475-1477.
