摘要
目的:探讨2型糖尿病合并骨质疏松的发病率并分析其发生的相关因素。方法:利用超声骨密度测定仪,检测2型糖尿病患者的骨质疏松情况,通过对2型糖尿病合并骨质疏松患者的年龄、病程、糖化血红蛋白(glucosylatedhemoglobin,HbA1c)、胰岛素敏感性指数(insulinsensitivityindex,ISI)、体质量指数(bodymassindex,BMI)、尿微量白蛋白等指标的分析,以了解2型糖尿病合并骨质疏松的危险因素。结果:在所有患者中,2型糖尿病合并骨质疏松患者平均空腹血糖、平均HbA1c犤(11.9±3.1)mmol/L,(9.9±1.3)%犦与未合并骨质疏松患者犤(9.3±2.2)mmol/L,(8.7±1.0)%犦比较,差异有显著性意义(t=2.13,2.09,P<0.05);合并与未合并骨质疏松患者平均病程、BMI比较,差异有显著性意义(t=2.18,2.33,P<0.05)。结论:高血糖、低BMI和病程长为2型糖尿病合并骨质疏松的高危险因素。
AIM:To explore the incidence rate of osteoporosis in type 2 diabetics,and to analyze its related factors. METHODS:Osteoporosis was determined by using ultrasonic bone densitometer in patients with type 2 diabetics.The age,disease course,glucosylated hemoglobin(HbA1c),insulin sensitivity index(ISI),body mass index(BMI) and urinary microalbumin were analyzed in type 2 diabetics with osteoporosis,so as to study its risk factors. RESULTS:The mean fasting blood glucose and HbA1c in the type 2 diabetic patients with osteoporosis[(11.9?à3.1￡(c)mmol/L,￡¨9.9?à1.3￡(c)%] were significantly different from those in the type 2 diabetic patients without osteoporosis[(9.3?à2.2￡(c)mmol/L￡?￡¨8.7?à1.0￡(c)%] (t=2.13,2.09,P< 0.05).The mean disease course and BMI were significantly different between the patients with or without osteoporosis(t=2.18,2.33,P< 0.05). CONCLUSION:Hyperglycemia,low BMI and long disease course are the high risk factors of osteoporosis in type 2 diabetics.
出处
《中国临床康复》
CSCD
2004年第21期4310-4311,共2页
Chinese Journal of Clinical Rehabilitation
