摘要
目的 探讨超声造影剂SonoVue在彩色多普勒超声造影诊断肝肿瘤中的应用。方法 对 3 2例肝占位性病变 (直径 11～ 112mm ,平均 43mm ;其中良性 13例 ,恶性 19例 )进行彩色多普勒超声造影 ,造影剂采用SonoVue ,浓度 5mg/ml,观察造影后肝肿瘤内血流增强情况。 结果 良性病变血流显示率由造影前的 5 3 .8%提高到造影后的 76.9% ,恶性病变血流显示率则由 78.9%提高到 10 0 %。肝肿瘤诊断符合率造影前为 75 .0 % ( 2 4/3 2 ) ,造影后为 90 .6% ( 2 9/3 2 )。结论 SonoVue彩色多普勒超声造影反映肝肿瘤内的血供情况有较高的敏感性和特异性 ,对肝肿瘤的鉴别诊断及提高诊断准确性有较大帮助。
Objective To investigate the diagnosis of hepatic tumors by contrast-enhanced color Doppler ultrasonography. Methods Thirty-two patients with known focal liver lesions(diameter 11-112 mm,mean 43 mm) were studied with color Doppler flow imaging(CDFI) before and after injection of 2.4 ml SonoVue at the concentration of 5 mg/ml. The pathological diagnosis included 13 benign lesions and 19 malignant ones. Analysis was performed on signal intensity of intratumoral vascularity,time of enhancement duration,resistant index and maximum velocity of intratumoral arterial blood flow. The data were compared between benign and malignant lesions. Results Before injection of SonoVue,intratumoral blood flow could be detected among 53.8 %(7/13) benign lesions and 78.9 %(15/19) malignant tumors. However these detection rates went up to 76.9 %(10/13) and 100%(19/19) respectively after administration of SonoVue. Significant difference between benign and malignant tumors was observed in time of enhancement duration. Furthermore RI showed significant difference between benign and malignant lesions.Diagnostic accuracy of hepatic tumors increased from 75.0 %( 24/32 ) to 90.6 %(29/32) after enhancement. Conclusions The clinical results showed the ability of contrast-enhanced CDFI in reflecting the blood supply of the hepatic tumors,demonstrating the high sensitivity and specificity of the technique,which could be of great value to the diagnosis of hepatic tumors.
出处
《中华超声影像学杂志》
CSCD
2004年第7期508-510,共3页
Chinese Journal of Ultrasonography
