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CD4^+T细胞在大鼠肠道各段IEL与LPL中的分布差异 被引量:4

Differences of distribution between CD4^+ IEL and LPL in intestinal trace of mature rat
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摘要 目的 探讨CD4 + 淋巴细胞在抗原诱导下的黏膜免疫应答中的作用。方法 采用免疫组织化学方法及光镜观察成年大鼠肠道各段IEL与LPL的形态和分布特征。结果 CD4 + T细胞在IEL与LPL中均沿十二指肠、空肠、回肠、结肠递增 ;LPL以CD4 + T细胞为主。结论 CD4 + Objective To find out the action of CD4 + lymphocytes in mucous immune responses under antigen inducement.Methods Used immunohistochemistry methods and electron microscope to observe the shape and the distribution of IEL and LPL which come from the mature rat.Results CD4 + IEL and LPL increased along the duodenum,jejunum,ileum and sigmoid flexure;the majority of LPL was CD4 +T cell.Conclusion The differences of CD4 + T cells' distribution are obvious among every state of intestine.
出处 《哈尔滨医科大学学报》 CAS 2004年第4期343-344,347,共3页 Journal of Harbin Medical University
关键词 上皮内淋巴细胞 固有层内淋巴细胞 黏膜免疫 免疫组织化学方法 IEL LPL mucosal immunity immunohistochemistry
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  • 1Walker WA. Breast milk and the prevention of neonatal and preterm gastrointestinal disease states; a new perspective[J]. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi, 1997,38(5):321-331.
  • 2Pulimood AB, Mathan MM, Mathan Ⅵ. Quantitative and ultrastructural analysis of rectal mucosal mast cells in acute infectious diarrhea[ J].Dig Dis Sci, 1998,43(9) :2111-2116.
  • 3Kuo S, EI Guindy A, Panwala CM, et al. Differential appearance of T cell subsets in the large and small intestine of neonatal mice[ J]. Pediatr Res,2001,49(4) :543-551.
  • 4Beagley KW, Fujihashi K, Lagoo AS, et al. Differences in intraepithelial Iymphocyte T cell subsets isolated from murine small versus large intestine[ J]. J Immunol, 1995,154( 11 ) :5611-5619.
  • 5Staats HF, Nichols WG,Palker TJ. Mucosal immunity to HIV-1:systemic and vaginal antibody responses after intranasal immunization with the HIV- 1 C4/V3 peptide T1 SP10 MN(A) [ J]. J Immunol, 1996,157( 1 ):462-472.

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