摘要
目的 :研究新生儿瞬态诱发耳声发射 (transientotoacousticemissions,TEOAE)和畸变产物耳声发射 (distor tionproductotoacousticemissions,DPOAE)听力筛选的最佳时机。方法 :对 2 0名正常新生儿出生后 15d每日进行TEOAE和DPOAE测试 ,并对其中 5名新生儿在出生后 4～ 6周进行复查 ,分析耳声发射 (OAE)检出率、反应幅值及测试时间等与天龄的关系。结果 :在新生儿出生后的最初几天里 ,随新生儿天龄的增加 ,TEOAE的检出率及反应幅值逐渐提高。新生儿 1～ 2d的检出率显著低于 3～ 5d ,出生后第 3d ,TEOAE检出率达到 97.4 % ,反应幅值也趋于稳定。随新生儿天龄的增加 ,DPOAE各测试频率的检出率也逐渐提高 ,0 .5kHzDPOAE的检出率始终较低且结果不稳定。出生后第 3d ,DPOAE检出率及反应幅值均趋于稳定。 1～ 5d的新生儿的平均测试时间为 5～ 10min。 4～ 6周后复查时 ,TEOAE和DPOAE的检出率为 10 0 %且反应幅值十分稳定 ,而测试时间需 4 0min以上。结论 :新生儿OAE听力筛选的应在其出生后 3d或 3d以上 ,但不宜太久。 0 .5kHz不宜作为DPOAE的听力筛选频率。对 4～ 6周后需要复查的新生儿 ,可考虑给予适量镇静剂。
Objective: To explore the optimal time of otoacoustic emissions(OAE) in newborn hearing screening. Methods:Transient otoacoustic emissions (TEOAE) and distortion product otoacoustic emissions (DPOAE) were recorded daily from 1 to 5 days postpartum in 40 ears of twenty health newborns with CELESTA 503 Cochlear Emission Analyzer. Five neonates among them were re examinated after 4 to 6 weeks postpartum. Results:The prevalence response levels of TEOAE and DPOAE gradually increased from the first day postpartum. The prevalence of TEOAE in 1 or 2 days was significantly lower than that in the following days. It rise to 97.4% in the age of 3 days postpartum and response levels tended to stability. The prevalence of DPOAE was lower and the response was not stable at the f 0 frequency of 0.5 kHz. While the f 0 was equal to or higher than 0.75 kHz, both the prevalence and response levels tended to stability in the age of 3 days. The mean test time was 5~10 min in the age of 1~5 days. When they were re examinated after 4 to 6 weeks postpartum, the prevalence of TEOAE and DPOAE were 100% and the response levels were very stable. But the mean test time increased to more than 40 min. Conclusion:The optimal time for performing TEOAE and DPOAE screening in newborns is at least 3 days after they were born. 0.5 kHz is not feasible for newborn as DPOAE hearing screening frequency.
出处
《武汉大学学报（医学版）》
CAS
2004年第5期577-580,共4页
Medical Journal of Wuhan University
关键词
耳声发射
听力筛选
新生儿
newborn
otoacoustic emissions
hearing screening
