摘要
目的 探讨猪、羊、鸡群中抗 HEV抗体流行率。方法 从新疆、广西、广东、北京和河北收集猪、羊、鸡的血清标本 4 98份 ,应用双抗原夹心酶联免疫法 (ELISA)检测抗 HEV抗体。结果 猪抗 HEV阳性率为 6 7 5 3% (10 4 15 4 ) ,其中新疆 4～ 5个月龄猪血清抗 HEV阳性率为 10 0 0 0 % ,广西 3个月龄以下仔猪抗 HEV阳性率为 36 0 0 % (9 2 5 ) ,6月龄以上猪阳性率为 71 6 7% (86 12 0 ) ;新疆 10 8份绵羊血清抗 HEV抗体全部阴性 ;2 36份鸡血清标本的抗 HEV阳性率仅为 1 2 7% (3 2 36 )。广东罗定、深圳和广西柳州郊区鸡血清标本中各检测出一份抗 HEV阳性 ,阳性率分别为 4 0 0 % (1 2 5 )、1 4 9% (1 6 7)、1 4 9% (1 6 7)。北京郊区 2 5份和河北 5 2份鸡血清抗 HEV检测全部阴性。结论 猪、鸡群中存在HEV感染 ,猪抗 HEV抗体流行率最高。猪和鸡在传播人HEV中的作用值得进一步研究。
Objective To investigate the prevalence of anti-HEV among swine,sheep and chickens. Methods Totally 498 sera of swine,sheep and chickens collected from Xingjiang,Guangxi,Guangdong,Beijing and Hebei were detected for the anti-HEV by an enzyme linked immunoassay. Results The anti-HEV positive rate of swine was 67.53%(104/154),in pigs between 4-5 months of age the rate was 100.00%(9/9) from Xingjiang. The rate in pigs under 3 months of age from Guangxi was 36.00%(9/25) and in pigs older than six months of age was 71.67% (86/120),respectively. The 108 sera of sheep collected from Xingjiang were all negative.The positive rate of chickens was only 1.27% (3/236). The anti-HEV prevalence rates of chickens from Luoding,Shenzhen,Liuzhou,beijing and Hebei were 4.00%,1.49%,1.49%,0,0 respectively. Conclusion HEV infection does exist among swine and chickens. The anti-HEV prevalence of swine was the highest among domestic animals. The role of swine and chickens in transmission of HEV needs to be further studied.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
北大核心
2004年第2期127-128,共2页
Chinese Journal of Experimental and Clinical Virology
基金
北京大学"九八五"项目资助课题
