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血浆乳酸测定及其在儿科急腹症中的应用

Application of plasma lactate measurement in children with acute abdominal pains
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摘要 目的 探讨急腹症患儿血浆和腹腔液乳酸测定对小儿急腹症鉴别诊断的意义。方法 用乳酸快速测定仪检测 6 1例急腹症患儿 ,其中腹膜炎组 33例 ,包括绞窄性肠梗阻 3例、肠穿孔腹膜炎 7例、阑尾炎穿孔脓肿2 3例 ;非腹膜炎组 2 8例 ,包括单纯性肠梗阻 8例、肠系膜淋巴结炎 7例 ,单纯性或早期化脓性阑尾炎 1 3例。结果 腹膜炎组血浆乳酸值 [(5 .37± 2 .4 0 )mmol/L]明显高于非腹膜炎组 [(3.71± 1 .0 0 )mmol/L ,P <0 .0 0 1 ];腹膜炎组腹腔液乳酸值 [(1 1 .93± 4 .1 7)mmol/L]明显高于非腹膜炎组 [(4 .2 5± 0 .97)mmol/L ,P <0 .0 0 1 ];腹膜炎组腹腔液 -血浆乳酸的差值均≥ 2 .75mmol/L ,非腹膜炎组 <1 .6 5mmol/L ;腹膜炎组的腹腔液乳酸值水平明显高于血浆乳酸值 (P <0 .0 0 1 )。结论 血浆和腹腔液乳酸的快速测定对小儿急腹症的鉴别诊断有重要意义。 Objective To study the measurement of lactate concentration in plasma and abdominal cavity fluid and its clinical significance in differential diagnosis for pediatric acute abdominal pains. Methods Lactate concentrations were measured in 61 children with acute abdominal pains. Among them there were 33 peritonitis including 3 intestinal obstructions, 7 perforative peritonitis and 23 appendicitis with abscess; 28 non peritonitis including 8 simple intestinal obstructions, 7 mesentery lymph node infection and 13 simple appendicitis. Results Plasma concentration of lactate in patients with peritonitis was significantly higher than that from non peritonitis cases [(5.37±2.40) mmol/L vs (3.71 ±1.00)mmol/L, P < 0.001]. In peritonitis patients the lactate concentration in abdominal cavity fluid from peritonitis patients was significantly higher than that from non peritonitis patients [(11.93±4.17)mmol/L vs (4.25± 0.97) mmol/L, P <0.001)]. The lactate concentration in abdominal cavity fluid was significantly higher than that in plasma ( P <0.001). Conclusions The rapid determination of plasma lactate concentration has important significance in differential diagnosis of acute abdominal pains in children.
作者 张力 沈霞
出处 《检验医学》 CAS 北大核心 2004年第4期315-317,共3页 Laboratory Medicine
关键词 血浆 乳酸测定 儿科 急腹症 腹腔液 腹膜炎 Lactate Plasma Abdominal cavity fluid Peritonitis
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参考文献7

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