摘要
目的:制备并探讨黄连药膜对慢性牙周炎的辅助治疗作用。方法:应用黄连水提取物制备药膜;将30例患有中到重度慢性牙周炎患者的各4颗牙随机分为4组:黄连药膜组、碘甘油组、空白药膜对照组和空白对照组。在基线、4周和7周时分别检测菌斑指数(PI)、探诊深度(PD)、附着丧失(AL)和探诊出血(BOP)等牙周病的临床指标。对资料进行方差分析和卡方检验。结果:各组在4周和7周时,探诊深度、附着丧失和探诊出血与基线比较均有显著性差异(P<0.05);黄连药膜组治疗效果优于其他各组(P<0.05),且治疗结束后,各项指标呈继续改善状态。结论:机械治疗后,应用黄连药膜辅助治疗,可以显著提高牙周炎的治疗效果。
PURPOSE: To make a therapeutic membrane with aqueous extract from coptis root and explore its adjunctive effects for treating chronic periodontitis. METHODS: Drug membrane from coptis root aqueous extract was developed; 4 teeth in 30 patients with moderate to advanced periodontitis were randomly divided into four groups: coptis root membrane, iodine glycerin, single drug membrane and blank control group. All parameters including plaque index (PI), probing depth(PD), attachment loss(AL) and bleeding on probing (BOP)were measured at baseline, 4 and 7 weeks after treatment. Analysis of variance and chi-square test were carried out for analysis. RESULTS: In all four groups, there were significant differences of PD, AL, BOP between baseline and 4,7 weeks after treatment(P < 0.05), the treatment effect of coptis root membrane was significantly superior to that of other three groups (P < 0.05). Moreover, all the parameters improved continuously. CONCLUSION: Use of coptis root membrane as an adjunctive method after scaling can significantly improve the treatment effect of periodontitis.
出处
《上海口腔医学》
CAS
CSCD
2004年第4期252-255,共4页
Shanghai Journal of Stomatology
关键词
黄连
牙周病
刮治
根面平整
Coptis root
Periodontal diseases
Scaling
Root planning
