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引导组织再生应用于牙种植体即刻种植的实验研究──可吸收膜与不可吸收膜的比较 被引量:3

Guided Tissue Regeneration Around Dental Implants in Immediate Extraction Sockets:Comparison of Resorbable and Nonresorbable Membranes
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摘要 本研究观察并比较了两种可吸收膜和一种不可吸收膜作为引导组织再生(GTR)膜应用于牙种植体即刻种植的引导成骨能力。结果表明:防止术后创口感染和膜暴露是GTR应用于即刻种植取得成功的关键;e-PTFE膜和胶原膜具有较好的引导成骨能力,并能促进种植体与周围骨组织间骨性结合的形成;由于胶原膜不引起明显炎症反应,并具有可吸收性而无需在植入后作二次手术取出,其可取代目前普遍使用的e-PTFE膜应用于临床,而polyglactin910膜因其具有较高的水后感染率和较低的引导成骨能力,似不宜作为GTR膜应用于牙种植体的即刻种植。 This study was performed to compare the efficacy of guided tissue regeneration (GTR) around dental implants immediately placed into extraction sockets by resorbable or nonresorbable membranes. Methods Mandibular P2, P3, and P4 of four adult beagle dogs were extracted bilaterally, and buccal standard defects were created and measured. Eighteen commercially pure titanium Steri-Oss implant fixtures were placed into the fresh extraction sockets. Four untreated implants were as controls, four implants received polytetrafluoroethylene (e-PTFE, Gore-Tex) membranes, five implants received collagen membranes, and five implants received polyglactin 910 mesh. After 14 weeks, clinical measurements were taken and the dogs were sacrificed and all specimens retrieved for histologic and histomophometric evaluation. Results The average gain in bone height was 2. 1 mm for untreated control sites, 3. 3 mm for Gore-Tex sites, 3. 8 mm for collagen sites, and 1. 3 mm for polyglactin 910 sites. Conclusion The results of this study indicated that Gore-Tex and collagen membrane produced good results for GTR around implants. Collagen membrane can bea valid alternative to Gore-Tex membrane to improve bone regeneration around dental implants, while polyglactin 91O mesh seemed not suitable to be used as GTR membrane in immediate implantation for its high infection rate.
出处 《中国医学科学院学报》 CAS CSCD 北大核心 1997年第6期436-441,共6页 Acta Academiae Medicinae Sinicae
关键词 引导组织再生 牙种植体 即刻种植膜 骨缺损 guided tissue regeneration membrane dental implants
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同被引文献35

  • 1耿威,宿玉成,徐刚,林润台.Bio-oss结合Bio-gide修复牙种植体周围骨缺损的组织学研究[J].口腔医学研究,2005,21(1):4-7. 被引量:23
  • 2张子军,卢世璧.引导性骨组织再生的初步实验研究[J].中华实验外科杂志,1995,12(1):59-59. 被引量:16
  • 3张浩.引导性组织再生膜材料的研究进展[J].国外医学(生物医学工程分册),1997,20(1):21-24. 被引量:7
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