摘要
目的 :研究绝经前期ⅡB～ⅣA期宫颈癌综合治疗的疗效。方法 :对 98例绝经前期ⅡB～ⅣA期宫颈癌患者的临床资料进行回顾性分析 ,比较≤ 3 5岁和 >3 5岁患者的生存率及手术组和非手术组综合治疗的疗效。结果 :98例绝经前期ⅡB～ⅣA期宫颈癌 2、3和 5年生存率分别为 60 2 0 %( 5 9/98)、47 96% ( 4 7/98)和 3 1 2 5 % ( 3 1/98) ,各期 5年生存率分别为ⅡB 5 8 82 % ( 10 /17)、ⅢA 3 4 0 4% ( 16/4 7)、ⅢB 17 3 9% ( 4 /2 3 )、Ⅲ2 8 5 7% ( 2 0 /70 )和ⅣA 9 0 9% ( 1/11)。比较手术组与非手术组综合治疗各期宫颈癌 5年生存率 ,差异有统计学意义 ,P <0 0 5。≤3 5岁组与 >3 5岁组 5年生存率分别为12 5 0 % ( 6/4 8)和 5 0 0 0 % ( 2 5 /5 0 ) ,差异有统计学意义 ,P <0 0 0 1。结论 :≤ 3 5岁绝经前期ⅡB～ⅣA期宫颈癌生存率低 ,年龄是影响预后的重要因素 ,手术治疗效果差 ,放射治疗仍是主要治疗手段 ,放射治疗后顽固肿瘤病灶可通过介入化疗或静脉化疗提高疗效。
OBJECTIVE:To investigate the curative effect of integrative treatment of premenopause carcinoma of cervix uteri of ⅡB-ⅣA. METHODS: The retrospective analysis was performed in 98 cases of premenopause carcinoma of cervix uteri between ⅡB and ⅣA. The survival rate and curative effect of integrative treatment were compared in patients whose age>35 years and ≤35 years.RESULTS: The 2-,3- and 5-year survival rates in premenopause carcinoma of cervix uteri of ⅡB-ⅣA were 60.20%(59/98),47.96%(47/98) and 31.25%(31/98). The 5-year survival rate in patients was ⅡB 58.82%(10/17),ⅢA 34.04%(16/47),ⅢB 17.39%(4/23),Ⅲ 28.57%(20/70) and ⅣA 9.09%(1/11)。The 5-year survival rates of different stages of surgery were compared with radiotherapy, there was a significant difference,P<0.05.The 5-year survival rate in patients whose age ≤35 years was 12.50%(6/48). The 5-year survival rate in patients whose age >35 years was 50.00%(25/50).The difference between the two groups was significant,P<0.001. CONCLUSIONS: The survival rate in premenopause carcinoma of cervix uteri of ⅡB-ⅣA whose age ≤35 years is low, The patients’ age is the important factor.The curative effect of surgery is poor. The radiotherapy is the primary way and the chemotherapy by vein or interposition can improve the curative effect of ⅡB-ⅣA.
出处
《肿瘤防治杂志》
2004年第9期952-954,共3页
China Journal of Cancer Prevention and Treatment
