摘要
目的 :观察布地奈德气雾剂吸入治疗喘息性支气管炎临床效果。方法 :5 3例慢性喘息性支气管炎患者随机分为观察组 (2 9例 )、对照组 (2 4例 ) ,在抗感染、平喘等治疗的基础上观察组给予布地奈德气雾剂吸入治疗 6周。所有病例治疗前后测定第 1秒用力呼气容量 (FEV1)、用力肺活量 (FVC)、FEV1占FVC的百分数 (FEV1/FVC % )和最大呼气流量 (PEF) ,观察临床疗效。结果 :两组临床症状改善无明显差异 (P >0 .0 5 ) ,FEV1、FVC、FEV1/FVC %治疗前后变化显著 (P <0 .0 5 ) ,PEF变化不明显。对照组各项指标在治疗前后无显著变化 (P >0 .0 5 )。结论 :布地奈德吸入治疗喘息性支气管炎能够改善患者肺功能 。
Objective:To observe the clinical efficacy of budesonide inhalation in treating patients with chronic asthmatic bronchitis. Methods: Fifty-three patients with chronic asthmatic bronchitis were randomly divided into budesonide group (29 cases) and control group (24 cases). On the basis of anti-infectious and antiasthmatic treatment, patients in budesonide group were given budesonide inhalation for 6 weeks. FEV_(1), FVC, FEV_1/FVC%, PEF were detected before and after treatment in all cases. The clinical efficacy was observed. Results: The clinical symptoms in budesonide group showed no significant improvement (P>(0.05)). It showed significant improvement in FEV_(1), FVC, FEV_(1)/FVC%, (P<(0.05)), but not in PEF. There is no significant changes in control group (P>(0.05)). Conclusion: Budesonide inhalation can significantly improve pulmonary function in patients with chronic asthmatic bronchitis, but no short-term clinical beneficial effect was observed.
出处
《内科急危重症杂志》
2004年第3期129-130,142,共3页
Journal of Critical Care In Internal Medicine
关键词
喘息性支气管炎
布地奈德气雾剂
肺功能
疗效
Asthmatic bronchitis Budesonide Pulmonary function Therapeutic efficacy
