摘要
本文检测了41株革兰氏阴性条件致病菌的药敏和R质粒。结果表明,耐3种以上抗生素的菌株达97.6%,而只耐2种抗生素的菌株仅占2.4%;41株均耐氨基苄青霉素;其中16株检出R质粒占,39%。通过耐药谱与转移的耐药基因分析表明,耐药性基因虽不完全由R质粒携带,但R质粒转移是细茵获得耐药性的主要机制之一。
This paper describes detection of drug sensitivity and conjugative R plasmid for 41 strains gram-negative opportunistic bacteria . It was found that the drug resistance was serious, 97.6% of those strains resisted to 3 agents or more, and conjugative R plasmid were detected in 16 strains, occupying 39% of all detected strains. The analysis of antibiograms and conjugative R plasmid revealed that: it is not all gene of drug resistance on conjugative plasmid, but R plasmid transfer is one of mechanisms for drug resistance acquired by bacteria.
出处
《哈尔滨医科大学学报》
CAS
1993年第1期37-39,共3页
Journal of Harbin Medical University
关键词
致病菌
革兰氏
阴性杆菌
R质粒
Opportunistic pathogen
Gram negative bacterium
R plasmid.