摘要
目的 观察辛伐他汀联合鲁南欣康对不稳定型心绞痛的治疗效果。方法 对 72例血清胆固醇及甘油三酯水平正常的不稳定型心绞痛患者随机分成两组———治疗组和对照组 ,治疗组 (n =36 )予以辛伐他汀联合鲁南欣康静滴治疗 ,对照组 (n=36 )予以安慰剂联合鲁南欣康静滴治疗 ,观察两组疗效。结果 治疗组总有效率 94 % ,对照组总有效率 6 7% ,两组间差异显著 (P <0 .0 1)。结论 辛伐他汀联合鲁南欣康治疗不稳定型心绞痛疗效明显 ,辛伐他汀具有调脂以外的抗心肌缺血作用。
Objective To evaluate the therapeutic effects of simvastatin and isosoribide 5-mononitrate on unstable angina pectoris. Methods Seventy-two patients with unstable angina pectoris and with normal serum TG and TC were randomly divided into two groups (treatment and control groups).In treatment group(n=36),patients were treated with simvastatin and isosoribide 5-mononitrate and in conrtol group(n=36) with plasibo and isosoribide 5-mononitrate. The results between both groups were compared. Results The effective rate was 94% in treatment group and 67% in control group. The effective rate of treatment group was significantly higher than that in control group(χ 2=7.18 ,P<0.01). Conclusion Simvastatin and isosoribide 5-mononitrate is more efficient than isosoribide 5-mononotrate alone to treat the unstable angina pectoris.Simvastatin has the function of anti-myocardial ischemia except adjusting dyslipidemia.
出处
《山西医科大学学报》
CAS
2004年第5期476-477,共2页
Journal of Shanxi Medical University
关键词
辛伐他汀
鲁南欣康
心绞痛
不稳定型
simvastatin
isosoribide 5-mononitrate
angina, unstable
