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固定化酶管式热敏传感器的数学模型及其应用——发酵产物浓度的测定 被引量:1

Modeling of Tubular Heat-Sensitive Sensor with Immobilized Enzyme and Its Application to the Determination of Fermentation Substance Concentration
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摘要 利用微元段内的物料与热量平衡,对固定化酶管式热敏传慈器进行了考察,建立了用联立双曲型偏微分方程组描述的数学模型。该模型用于具体的发酵产物浓度测试,所得出的输入浓度与输出温差之间的关系具有Monod方程的形式,其度化趋势较好地反映了实测结果。 By means of the material and energy balances, this paper establishes a mathematical model to describe the tubular hot-sensitive sensor with immobilized enzyme. It involves a set of hyperbolic partial differential equations, and can be used to determine the concentration of fermentation substances. The obtained relationship of ingoing concentration vs. outgoing temperature difference has the form of MONOD equation, and is in good agreement with the experimental results.
出处 《华东化工学院学报》 CSCD 1993年第1期72-78,共7页
关键词 固定化酶 数学模型 热敏传感器 immobilized enzyme penicilin concentration mathematical model enzyme thermistor device concentration determination
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同被引文献9

  • 1鲍景旦,恽瑛,虞大红.酶热敏装置[J].大学化学,1993,8(6):38-40. 被引量:1
  • 2鲍景旦,虞大红,恽瑛,陈淑章.用酶热敏法测定青霉素浓度[J].华东化工学院学报,1993,19(4):519-523. 被引量:1
  • 3张慧君,许学勤,徐斐,华泽钊.用于农药残留快速检测的两种酶的比较[J].分析化学,2004,32(11):1517-1520. 被引量:22
  • 4Danielsson B, Mattiasson B, Mosbach K. Enzyme Thermistor Devices and Their Analyticla Applications[J]. Appl Biochern bioeng, 1981,3 : 97-143.
  • 5Batillard P. Calorimetric Sensing in Bioanalytical Chemistry Principles, Application and Trends[J]. Trends in Analytical Chemistry, 1993,12 (10):387-394.
  • 6Xie B, Ramanathan K, Danielsson B. Principle of Enzyem Thermistor Systems: Application to Biomedical and Other Measurements[J]. Advances in Biochemical Engineering/ Biotechnology, 1999,64:1-33.
  • 7吴瑛.FLA农残速测酶传感器的参数优化研究[D].上海理工大学硕士论文,2006.3.
  • 8华泽钊 肖建军 徐斐 中华人民共和国国家知识产权局.探测农药残留用的量热式生物传感器[P].012538876.2002-11-06.
  • 9赵肖磊,郑艺华,王芳芳,华泽钊.酶法测定农药残留量的量热系统的初步实验研究[J].食品科学,2004,25(2):127-130. 被引量:9

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