摘要
目的 了解广州地区淋球菌对抗生素的耐药性及PPNG和TRNG的流行状况。方法 用琼脂稀释法测定最低抑菌浓度 (MIC)以及用纸片碘量法检测 β 内酰胺酶。 结果 116株淋球菌检出PPNG30株 (2 5 9% )、TRNG36株 (31% )、环丙沙星耐药率达 93 1% ,头孢三嗪、壮观霉素未发现耐药菌株 ,且抗菌活性最强。
Objective To survey the antibiotic resistance and the prevalence of PPNG and TRNG in Guangzhou Method Minimum inhibitory concentrations(MIC)to penicillin G,tetracycline,ciprofloxacin,ceftriaxone and spectiomycin were determined using the agar dilution method,and β-lactamase by paper iodin quantitative method.Results 30 strains of Neisseria gonorrhoeae produced β-lactamase.while 36 showed plasmid-mediated,high-level resistance to tetracycline(TRNG).Resistant rates of ciprofloxacin was as much as 93.1%.There was no resistance to ceftriaxone and specitinomycin.The ceftriaxone and specitnomycin activity is stronger.Conclusion The study showed that it is important to successively survey the antibiotic resistance of Neisseriae gonorrhoeae.
出处
《中国微生态学杂志》
CAS
CSCD
2004年第5期311-311,313,共2页
Chinese Journal of Microecology
