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大鼠大脑中动脉的衰老性变化 被引量:5

Aging changes of middle cerebral artery in rats
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摘要 目的 :观测大鼠大脑中动脉的衰老性变化。方法 :在常规光镜、透射电镜下观察 ,并应用图像分析系统作测量。结果 :衰老后 ,大鼠大脑中动脉管壁厚度几乎无改变 ,管腔增大 ;平滑肌细长 ,内弹性膜变薄、断裂、分层及脂质沉积。结论 Objective: To study the aging changes of the middle cerebral artery in rats. Methods:Light microscope, electron microscope and image analysis system were used.Results:In aged group, the main result observed was a significant increase in middle cerebral arterial lumen size, but the arterial wall thickness had no obvious changes. The smooth muscle cell got slender, the internal elastic laminae became thinner, delaminated and disrupted, and the lipid deposited . Conclusion:Both shape and ultrastructure are changed remarkablely in middle cerebral artery of aged rats.
作者 文灿 朱星红
出处 《解剖学杂志》 CAS CSCD 北大核心 2004年第5期528-530,567,共4页 Chinese Journal of Anatomy
关键词 大脑中动脉 大鼠 衰老 改变 高龄 平滑肌 光镜 结论 变化 管壁厚度 middle cerebral artery aged rat
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