摘要
目的 :了解冠心病患者血脂及C 反应蛋白等炎症指标的变化规律。方法 :测定 5 1例冠心病患者和 72例正常对照者血清甘油三酯 (TG)、总胆固醇 (T CHO)、高密度脂蛋白胆固醇 (HDL C)、低密度脂蛋白胆固醇 (LDL C)、C 反应蛋白 (CRP)、血浆纤维蛋白原(Fg)及全血白细胞 (WBC) ,并进行统计学分析。结果 :冠心病患者TG、T CHO、HDL C、LDL C、CRP、Fg及WBC的结果分别为( 1 84± 1 0 3 )mmol/L、( 6 47± 1 88)mmol/L、( 1 0 7± 0 2 1)mmol/L、( 4 94± 1 2 6)mmol/L、( 7 42± 1 3 5 )mg/L、( 5 0 7± 0 84) g/L及 ( 8 5 9± 2 82 )× 10 9/L ,较正常对照者均有显著性差异 (P <0 0 1)。结论 :血脂异常是冠心病的主要危险因素之一 ;冠心病的发生与炎症反应相关 ,CRP、Fg及WBC可作为评价冠状动脉病变程度的一个参考指标。
Objective:To understand the changes in blood lipid,C-reactive protein and other inflammatory parameters in patients with coronary heart disease.Methods:Triglyceride(TG),total cholesterol(T-CHO),high density lipoprotein(HDL-C),low density lipoprotein(LDL-C),C-reactive protein(CRP),fibrinogen(Fg) and white blood cells (WBC)in 51 patients with coronary heart disease and 72 normal adults were examined and a statistical analysis was made.Results:TG,T-CHO,HDL-C,LDL-C,CRP,Fg and WBC in coronary heart disease were(1.84±1.03)mmol/L,(6.47± 1.88)mmol/L ,(1.07±0.21)mmol/L,(4.94±1.26)mmol/L,(7.42±1.35)mg/L,(5.07±0.84)g/L and (8.59±2.82)×10 9/L,which were all significantly different from those in the control group(P<0.01).Conclusions:Abnormal blood lipid is one of the important risk factors for coronary heart disease.Coronary heart disease was correlated with inflammatory response.CRP,Fg and WBC may be used as an index for the evaluation of the severity of coronary heart disease .
出处
《华北国防医药》
2004年第5期319-320,共2页
Medical Journal of Beijing Military Region
