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白三烯受体拮抗剂治疗哮喘的进展和临床评价 被引量：6

Progress and Clinical Evaluation of Leukotrienes Receptor Antagonists in the Treatment of Asthma
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摘要 目的 :评价白三烯受体拮抗剂在治疗哮喘中的进展和临床应用。方法 :检索国内外文献 ,对有关抗白三烯药物的文献进行分析、总结。结果 :近年来 ,高选择性白三烯受体拮抗剂进展十分迅速 ,其通过抑制白三烯合成和白三烯受体而对抗哮喘。结论 :该类药物为一类新型、安全和有效的抗炎和平喘药物 ,在防治成人和儿童的长期哮喘上展现了良好的治疗前景。 OBJECTIVE:Progress and clinical application of leukotrienes (LTs)receptor antagonists in the treatment of asthma were summarized.METHODS:The literatures about leukotrienes receptor antagonists at home and abroad were reviewed,analyzed and summarized.RESULTS:Advance in highly selected leukotrienes receptor antagonists has been swift in recent years. It could fight against asthma by inhibiting the synthesis of leukotrienes or antagonizing leukotrienes receptor. CONCLUSION:Leukotrienes receptor antagonists will be a new kind of safe and effective drugs in antiinflammation and anti-asthma. They have now been playing an important role in prevention and long-term therapy of asthma for adults and children.
作者 马永录 蒋坤 任耘
机构地区 天津医科大学总医院药剂科 天津医科大学药学系
出处 《中国医院用药评价与分析》 2004年第5期273-276,共4页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 哮喘 治疗 白三烯受体拮抗剂 临床评价 临床应用 抗白三烯药物 平喘药物 国内外 展现 目的 asthma leukotrienes leukotrienes receptor antagonist progress clinical evaluation
分类号 R562 [医药卫生—呼吸系统] R725 [医药卫生—儿科]
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参考文献18

  • 1[1]Jawien J, Chlopichi S, Olszanecki R, et al. Eosinophilepithelial cell interaction augents cysteinyl leukotrienes synthesis[J]. J Physiol Pharmacol, 2002,53(1): 127.
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  • 7张石革,马国辉.白三烯受体拮抗剂的作用与临床应用评价[J].中国医院用药评价与分析,2003,3(2):75-77. 被引量：4
  • 8翟振国,蒋捍东,秦筱梅.抗白三烯药物与哮喘现代治疗[J].青岛大学医学院学报,2003,39(1):103-105. 被引量：2
  • 9李善群,钮善福,姜丽岩,聂莉,陈琪,高文杰.扎鲁司特片治疗113例支气管哮喘的临床应用[J].临床肺科杂志,2002,7(1):4-6. 被引量：3
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二级参考文献21

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共引文献10

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二级引证文献29

中国医院用药评价与分析
2004年 第5期

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