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^(18)F-FDG PET对不典型肺结节良恶性鉴别诊断初步应用 被引量:2

^(18)F-FDG PET in differentiating malignant tumor from benign lesion in atypical pulmonary nodules
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摘要 目的 研究不典型肺结节18F FDGPET影像类型、显像特征及在良恶性鉴别诊断中的应用价值。方法 对 119例不典型肺结节行18F FDGPET显像 ,根据肺结节代谢水平和结节以外放射性摄取灶进行影像分型。结果 单发高代谢肺结节 (Ⅰ型 ) 72例、单发低代谢肺结节 (Ⅱ ) 3 5例、多发高代谢肺结节 (Ⅲ ) 6例及多发低代谢肺结节 (Ⅳ ) 6例。Ⅰa型、Ⅰb型、Ⅰd型多为恶性 ,诊断准确率分别为 90 .9%、95 .4%、10 0 % ;Ⅱa型和Ⅱb型良性居多 ,准确率为 91.6%和 92 .8% ,以上 5种亚型占全部病例 78.9%。结论 利用18F FDGPET代谢影像类型和特征 。 Objective To investigate the image patterns and characteristics of 18 F-FDG PET in atypical pulmonary nodules and differentiating malignant tumors from benign lesions existed in these nodules. Methods 18 F-FDG PET was performed on 119 cases with atypical pulmonary nodules in chest radiology. The image patterns and characteristics of PET were studied depending on glucose metabolism in pulmonary nodules and high uptake foci of FDG beyond the nodules. Results The image patterns were classified into 4 types: hypermetabolic solitary pulmonary nodules (typeⅠ), hypometabolic SPNs (Ⅱ), hypermetabolic multiple pulmonary nodules (Ⅲ) and hypometabolic MPNs (Ⅳ), which was found in 72, 35, 6 and 6 cases, respectively. Hypermetabolic SPNs alone (subtypeⅠa,11 cases), hypermetabolic SPNs complicated with high uptake foci in ipsilateral hilus of the lung and mediastinum (Ⅰb,22 cases), hypermetabolic SPNs complicated with very high uptake foci in remote sites (Ⅰd, 35 cases), hypometabolic SPNs alone (Ⅱa,12 cases) and hypometabolic SPNs complicated with slight high uptake foci in bilateral hili and mediastinum (Ⅱb,14 cases) were five common clinical subtypes (78.9% of these cases in total patients), and the diagnostic accuracy of PET were 90.9%,95.4%,100%,91.6% and 92.8%, respectively. Conclusion 18 F-FDG PET is recommended to be as the further examination for differentiating malignant tumors from benign lesions in atypical pulmonary nodules.
出处 《中国医学影像技术》 CSCD 2004年第10期1478-1481,共4页 Chinese Journal of Medical Imaging Technology
关键词 不典型肺结节 鉴别诊断 正电子发射体层摄影术 脱氧葡萄糖 Atypical pulmonary nodules Differential diagnosis Positron-emission tomography FDG
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