摘要
目的 观察 2型糖尿病患者颈动脉内膜中层厚度 (IMT)和血浆纤维蛋白原 (Fg)的变化 ,并探讨其相关性。方法 选择 112例 2型糖尿病患者 ,应用B超检测其颈动脉内膜中层厚度及斑块形成 ,同时测定血浆Fg含量 ,并与正常对照组比较。IMT及Fg行相关分析。结果 2型糖尿病患者IMT及Fg水平显著高于对照组 (P <0 0 1) ;IMT与Fg呈显著正相关 (P <0 0 1)。 结论 Fg在
Objective To investigate the relationship between carotid intima media thickness(IMT) and plasma fibrinogen(Fg) in patients with type 2 diabetes mellitus(T 2DM).Methods 112 patients were chosen and the level of plasma Fg was measured in these patients.Meanwhile,carotid IMT was observed with high resolution ultrasound,data of 35 healthy persons was taken as the control group.Results The levels of IMT and Fg in T 2DM group were higher than those in the control group.The T 2DM patients were divided into IMT≤0.9mm group,IMT>0.9mm group and plaque group.The concentration of plasma Fg was significantly increased in plaque group,compared with that in IMT≤0.9mm group and IMT>0.9mm group.Positive correlation was found between the concentration of plasma Fg and the level of IMT(P<0.01).Conclusion The level of plasma Fg was significantly increased in type 2 diabetic patients and correlated with the level of IMT.To T 2DM patients.Fg plays an important role in the progression of carotid atherosclerosis.
出处
《中国基层医药》
CAS
2004年第11期1291-1292,共2页
Chinese Journal of Primary Medicine and Pharmacy
