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SARS隔离区职业暴露后的跟踪观察及实验研究 被引量:1

Occupational Exposure in SARS Isolation Area:Observation and An Experimantal Study
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摘要 目的 探讨暴露于SARS病毒后的医务人员的危险程度和观察处理 ,了解SARS病毒是否经过血液传播 ,为今后从事SARS防治人员提供帮助和信息。方法 利用ELISA的方法检测 5例暴露者的SARS病毒抗体IgG和IgM ,并用流式细胞仪采用直接荧光染色法检测T细胞亚群。结果  5例暴露者的抗体检测均为阴性 ;T细胞亚群值都在正常范围。结论  5名暴露者没有受到SARS病毒的感染 ;但因暴露者的例数少 ,对检测时机的把握还要进一步摸索 ;因此还不能确定SARS病毒是否经过血液传播 ; OBJECTIVE To investigate SARS virus transmission via blood and to provide relevant information for health workers. METHODS The counts of T cell subset and the antibodies of IgG,IgM from the 5 health workers were done by flow cytometry and ELISA. RESULTS The antibodies of 5 victims were negative. The counts of T cell subset were detected in normal range. CONCLUSIONS Five persons are not infected by SARS virus. But we only have few cases. We can′t definite whether or not SARS virus transmission via blood and need advanced research. To evaluate the risk of post exposure also needs advanced discussion.
出处 《中华医院感染学杂志》 CAS CSCD 2004年第10期1118-1120,共3页 Chinese Journal of Nosocomiology
关键词 SARS 抗体 T细胞亚群 SARS Antibody T cell subset
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  • 1曹卉,柳青,明建扩.免疫调节剂对荷瘤小鼠红细胞免疫粘附功能及抑瘤生长的研究[J].济宁医学院学报,1996,19(1):24-26. 被引量:2
  • 2胥金章.我国研究出非典快速诊断技术2小时即可得结果[EB/OL].http://www.sina.com.cn/news,2003-04-16.
  • 3Julie Louise Gerberding, M D, M P H. Management of occupational exposures to blood-borne viruses[ J ]. N Engl J Med, 1995.332:444 -449.
  • 4John G Bartlett. MEDICAL CARE of PATIENTS WITH HIV INFECTION.Eighth Edition[J] .Williams & Wilkins, 1999.77 - 78.
  • 5Henderson DK, Fahey BJ, Willy M. et al. Risk for occupational transmission of human immunodeficiency virus type 1 associated with clinical exposures.A prospective evaluation. [J ] Ann Intern Med, 1990,113:740-746.
  • 6CDC. Public Health Service statement on management of occupational exposures human immunodeficiency virus, including considerations regarding zidovudine postexposure use[J ], . MMWR 1990, 39(RR-1 ) :1- 14.
  • 7Jerome I.Tokars, MD, MPH; Ruthanne Marcus, MPH; David H.Culver, PHD; Charles A.Schable, MS et al.Surveillance of HIV Infection and Zidoudine Use among Health Care Workers after occupational exposure to HIV-infected Blood[J] .Ann Intern Med, 1993,118:913-918.
  • 8Beekmann SE, Fahey BJ, Gerberding JL, et al.Risky business: using necessarily imprecise casualty counts to estimate occupational risks for HIV-1 infection[J]. Infect Control Hosp Epidemiol, 1990;11:371 -379.
  • 9Peiris J S M,Lai A T, Poon L L M et al. Coronavirus as a possible cause of severe acute respiratory syndrome[J]. Lancet,2003;361 : 1319-1325.
  • 10Drosten C,Gunther S,Preiser W,et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome[J/OL]. N Engl J Med,http://www. nejm. org,2003-04-10.

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