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肝胆管结石合并胆管癌的临床分析 被引量:27

Clinical analysis on hepatolithiasis combined with cholangiocarcinoma
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摘要 目的 探讨肝胆管结石合并胆管癌的诊治经验。方法 总结 1981~ 2 0 0 2年第三军医大学西南医院收治的 4 8例肝胆管结石合并胆管癌病人的临床资料。结果 术前CT检查诊断正确率为 80 % (2 8/ 35 ) ,其中6 0 7%为肝内病变 ;超声检查诊断率为 5 7 8% (2 6 / 4 5 ) ,其肝门病变的诊断正确率为 5 3 8%。根治性手术 13例 ,病理诊断为胆管腺癌及黏液癌。随访 2 2例 ,根治组平均存活 2 5个月 ,姑息治疗组平均存活 12个月。结论 胆管癌的发生与肝胆管结石有关 ;伴有结石的胆管癌疗效较差 ,应重视胆管结石的早期根治性治疗 ,以防止胆管癌的发生 ;姑息性手术可提高生活质量。 Objective To discuss diagnosis and treatment experience of hepatolithiasis combined with cholangiocarcinoma. Methods Data of 48 cases of hepatolithiasis combined with cholangiocarcinoma from 1981 to 2002 in Southwest Hospital of Third Military Medical University were collected.Results Preoperative CT diagnostic rate was 80% (28/35). Among them intrahepatic lesion accounted for 60.7%. Ultrasonography diagnostic rate was 57.8% (26/45). Among them porta hepatis lesion accounted for 53.8%. Thirteen cases of adenocarcinoma and mucocarcinoma in bile duct were radically resected. Twenty-two cases were followed up. The average survival time of patients performed radical resection was 25 months,and that of patients performed drainage was 12 months.Conclusion Cholangiocarcinoma may be related to hepatolithiasis.The therapeutic effect of cholangiocarcinoma combined with hepatolithiasis was poor. Early radical therapy for hepatolithiasis play a important role in preventing cholangiocarcinoma occurrence.Drainage therapy for cholangiocarcinoma may improve quality of live.
出处 《中国实用外科杂志》 CSCD 北大核心 2004年第8期485-487,共3页 Chinese Journal of Practical Surgery
关键词 肝胆管结石 合并症 胆管癌 超声检查 Hepatolithiasis Cholangiocarcinoma Drainage Radical resection
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