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新城疫病毒P基因的RNA编辑及其抗干扰素作用 被引量：7

The RNA Editing of Newcastle disease virus and the Accessory Proteins Function as Interferon Antagonist
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摘要 新城疫病毒的P基因转录过程中在第484特定位置插入非模板G碱基发生RNA编辑现象 ,产生两种非结构蛋白 ,即V和W蛋白。文章综述了副黏病毒 (主要是新城疫病毒 )P基因RNA编辑的机理。 The P gene of Newcastle disease virus encodes two accessory proteins including the V and W protein by means of inserting of non-template nucleotides and this is called RNA editing. The mechanism of RNA editing and the functions of the produced accessory proteins especially of the V protein of Newcastle disease virus were reviewed in this article.
作者 刘玉良 刘秀梵
机构地区 扬州大学农业部畜禽传染病学重点开放实验室
出处 《动物医学进展》 CSCD 2004年第6期1-3,共3页 Progress In Veterinary Medicine
关键词 新城疫病毒 P基因 RNA编辑 抗干扰素作用 Newcastle disease virus RNA editing antagonist
分类号 S852.659.5 [农业科学—基础兽医学]
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参考文献22

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同被引文献64

  • 1李翔,房慧伶,曾芸,兰宗宝.新城疫病毒人工感染鸡诱导胸腺和法氏囊细胞凋亡的初步研究[J].广西畜牧兽医,2005,21(2):51-53. 被引量：7
  • 2崔玉东,冉旭华,宋佰芬,朴范泽.新城疫病毒Ⅰ系毒株通过Caspase途径诱导鸡胚成纤维细胞凋亡[J].中国兽医学报,2006,26(3):254-256. 被引量：4
  • 3辛朝安,任涛,罗开健,张洁,杨佩琼.疑似鹅副粘病毒感染诊断初报[J].养禽与禽病防治,1997(1):5-5. 被引量：87
  • 4房慧伶,李翔,曾芸,王晓丽,韦英益,兰宗宝.新城疫病毒F48E8体内诱导鸡胸腺淋巴细胞凋亡的研究[J].畜牧与兽医,2007,39(4):17-19. 被引量：1
  • 5Czegledi A, Ujvari D, Somogyi E, et al. Third genome size category of avian paramyxovirus serotype 1 (Newcastle dis- ease virus) and evolutionary implications [J]. Virus Res, 2006, 120 (1-2) : 36-48.
  • 6Jahanshiri F, Eshaghi M, Yusoff K. Identification of phospho- protein: phosphoprotein and phosphoprotein..nucleocapsid pro- tein interaction domains of the Newcastle disease virus [J]. Arch Virol, 2005, 150(3): 611-618.
  • 7Huang Z, Krishnamurthy S, Panda A, et al. Newcastle dis- ease virus V protein is associated with viral pathogenesis and fimctions as an alpha interferon antagonist [J]. J Virol, 2003, 77 (16) : 8676.
  • 8Kim L M, King D J, Suarez D L, et al. Characterization of class I Newcastle disease virus isolates from Hong Kong live bird markets and detection using real-time reverse transcription-PCR [J]. J Clin Microbiol, 2007, 45 (4) : 1310-1314.
  • 9Yu S Q, Kishida N, Ito H, et al. Generation of vel ogenic Newcastle disease viruses from a nonpathogenic waterfowl isolate by passaging in chickens[J]. Virology, 2002, 301 (2) ~ 206-211.
  • 10Collins M J, Bashiruddin D, Alexander, et al. Deduced amino acid sequences at the fusion protein cleavage site of New- castle disease viruses showing variation in antigenicity and pathogenicity[J]. Arch Virol, 1993, 128 (3) : 363-370.

引证文献7

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动物医学进展
2004年 第6期

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