摘要
目的探讨宫壁置卡孕栓防治剖宫产产后出血的临床效果。方法选择160例足月剖宫产患者随机分为试验组及对照组。试验组80例,在胎儿娩出后立即于子宫下段前壁近切口处浆膜下置入卡孕栓1 mg;对照组80例,胎儿娩出后立即宫体注射催产素10 u及静滴20 u,观察产后2 h的出血量。结果第三产程试验组(3.75±3.4)min,对照组(5.4±3.0)min,两组比较,差异有显著性(P<0.01);产后2 h内平均出血量:试验组平均为134.2 ml,对照组平均为215 ml,两组比较,差异有显著性(P<0.01);用药前后血压变化不明显,术后两组的体温变化及切口愈合情况差异不明显。结论卡孕栓比催产素具有更强的子宫收缩作用,能减少产后出血量,而宫壁给药更有效更方便。
Objective: To observe the clinical effects of putting Methylcarboprost suppository on postpartum bleeding in normal parturients. Methods: One hundred and sixty normal parturients were randomized into study group (n=80) and the control group (n=80). Parturients in study group (n=80) were immediately administered 1mg Methylcarboprost suppository near the incision of perimetrium in anterior wall of lower segment of the uterus after the delivery of the fetus. The controls (n=80) were immediately given 10 u oxytocin via corpus uteri injection and 20u oxytocin via intravenous drip after the delivery of the fetus. The amount of bleeding within 2 hours postpartum was measured. Results: The third stage of labor of the study group lasts (3.75±3.4) min, the controls (5.4±3.0) min. By comparison, the differences in the third stage of labor between the two groups were statistically significant(P<0.01). The mean amount of bleeding within 2 hours′ postpartum in study group was 134.2 ml respectively. In contrast, the mean amount of bleeding within 2 hours′ postpartum in control group was 215 ml respectively. By comparison, the differences in the amount of bleeding within 2 hours′ postpartum between the two groups were statistically significant (P<0.01). The blood pressure before and after the injection doesn′t change greatly. After the operation the body temperature and the healing of the incision of the two groups show little sign of change between the two groups. Conclusion: Methylcarboprost suppository is more effective than oxytocin in controlling postpartum hemorrhage. And drug administration via the uterus wall is more effective and convenient to perform.
出处
《中国内镜杂志》
CSCD
2004年第11期92-94,共3页
China Journal of Endoscopy
关键词
产后出血
卡孕栓
宫壁置药
postpartum hemorrhage
methylcarboprost suppository
uterus wall
