摘要
目的 :研究汉语阅读障碍儿童汉字认知过程左前额叶皮层血氧变化规律 ,探讨阅读障碍发病机制的神经生理基础。方法 :以正常儿童做对照组 ,应用功能性近红外光学成像技术 (fNIRI)测查汉语阅读障碍儿童汉字初级加工及再加工过程左前额叶脑血氧变化。结果 :汉字初级加工的 4个过程 ,两组儿童左前额叶皮层都被激活 ,阅读障碍组儿童激活程度较对照组儿童高 (P <0 .0 5 ) ,在左前额的左侧区域表现最为明显 ;汉字再加工时词语输出的血氧值变化量 ,阅读障碍组儿童的血氧值变化量较对照组低 ,而语义联想过程 ,阅读障碍组儿童的血氧值变化量高于对照组儿童。结论 :汉字认知过程阅读障碍儿童左前额叶皮层虽然激活 ,但相对正常儿童 ,激活的程度和激活模式均有差异。
Objective:To investigate the regional cerebral blood oxygenation changes of left prefrontal lobe during dyslexic children recognizing Chinese characters. Methods:We use functional near-infrared imaging (fNIRI) technique to observe 28 dyslexic elementary school students and 19 healthy students who are not reading-impaired.Results:With fNIRI, significant activations were observed in the left prefrontal cortex of both dyslexic children and non-dyslexic children during primary processing of Chinese characters, and children with dyslexia were evoked more significantly ( P <0.05). During secondary processing, dyslexic children's left prefrontal cortex blood oxygenation were lower than that of the healthy children firstly, and then they increased notably.Conclusions:The evoked model of character cognition was different between these two groups of children. This result suggested the biological basis of the disorder.
出处
《中国临床心理学杂志》
CSCD
2004年第4期383-385,共3页
Chinese Journal of Clinical Psychology
基金
国家自然基金资助 (项目批准号为 3 0 4714 68)
