摘要
目的 :研究 2型糖尿病患者慢性牙周炎的龈下菌群以及菌群变化与血糖、糖化血红蛋白的关系。方法 :细菌学厌氧培养、PCR检测技术。结果 :2型糖尿病患者慢性牙周炎的龈下菌群以厌氧菌为主。产黑菌、二氧化碳噬纤维菌数量与糖尿病患者空腹血糖、糖化血红蛋白之间存在正相关关系。产黑菌、二氧化碳噬纤维菌数量随患者空腹血糖、糖化血红蛋白的升高而增加。结论 :2型糖尿病慢性牙周炎患者龈下菌斑相关菌与血糖。
Objective:To study the subgingival bacterium flora in chronic periodontitis patients with type-2 diabetes mellitus (DM-2), and the relation between the ratio of flora and the level of fasting plasma glucose(FPG) or glycosylated hemoglobin(GHb). Methods: Subgingival plaque samples were taken from 22 chronic periodontitis teeth in patients with DM-2 and 22 without DM-2. The samples were cultured by bacteria culture technique and identified by PCR and Bergey system.Clinical indexes,FPG and GHb were measured.Results:The clinical indexes of gingival index, periodontal index,probing depth,attachment loss,tooth looseness and bleeding on probing(BOP) and the subgingival bacteria flora typs in the 2 groups were not significantly different (P>0.05).The major germ of subgingival flora of the patients with DM-2 was anaerobe. Amount of black germs and Capnocytophaga was positively correlated with the level of FPG or GHb in the patients with DM-2(P<0.01). Conclusion:Black germs and capnocytophaga in chronic periodontitis patients are related to level of FPG or GHb.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2004年第6期747-749,共3页
Journal of Practical Stomatology
关键词
糖尿病
牙周炎
细菌
Diabetes mellitus
Periodontitis
Bacteria
