期刊文献+

人工髓核置换术治疗腰椎间盘突出症的临床初步报告 被引量:13

Prosthetic disc nucleus replacement in the treatment of lumbar disc herniation
原文传递
导出
摘要 目的介绍人工髓核置换术治疗腰椎间盘突出症的手术方法并评价其近期临床疗效。方法自2002年3~4月采用人工髓核置换术治疗腰椎间盘突出症患者9例,男6例,女3例;年龄22~48岁,平均33.4岁;病史8个月~3.6年,平均18.4个月。均为单间隙病变,以单纯腰痛为主者2例,腰痛伴一侧下肢放射痛或双侧下肢放射痛以一侧为主者7例。手术节段为L4,56例,L5S13例;后侧入路8例,经腹膜后侧前方入路1例。随访12~13个月,平均12.3个月。根据症状改善情况和影像学资料评价手术效果。结果手术时间45~120min,平均60min;术中出血50~150ml,平均120ml。术后4~5d戴腰围下地活动,术后6周去腰围恢复正常活动。根据Oswestry下腰痛和功能不利评分,临床成功率88.9%。复查X线片示术后和术前椎间隙高度百分比为128%。1例患者术后腰痛缓解不明显,第4d出现健侧下肢放射痛,经卧床、脱水治疗后缓解。2例随访时摄正侧位X线片示植入物轻度移位,未见腰椎生理弧度异常改变,腰椎活动度正常。未见植入髓核脱出、感染等并发症。结论人工髓核置换术在改善症状的同时能够增加椎间高度,维持腰椎的正常运动功能,近期临床疗效满意。 Objective To introduce the operative procedure of prosthetic disc nucleus(PDN)re-placement and investigate its clinical effectiveness in the treatment of lumbar disc herniation.Methods Nine cases of lumbar disc herniation were treated with PDN replacement from March2002to April2002.There were6males and3females,the average age of the patients was33.4years ranging from22to48years.The interval between the onset of the symptoms and the diagnosis was averagely18.4months,ranging from8months to3.6years.All of the patients were evaluated by anteroposterior and lateral radiography,computer-ized tomography and,if necessary,magnetic resonance imaging.The low back pain was predomi nant in two patients,the low back pain associated with radicular leg pain in6patients.The height of disc space became narrowed in varying grade.The operated level was at L 4-5 in6patients,L 5 S 1 in3patients.The standard pos-terior approach was used in8patients;the anterior lateral retroperitoneal approach was adopted in1patient.8cases were implanted with a single PDN,and1case with a couple of PDNs.Results All patients were followed up12to13months(average12.3months).The estimated intraoperative blood loss ranged from50to150ml (mean120ml ),and the total operation time ranged from45to120min(mean60min).The patients wore a brace for the first6weeks.Based on Oswestry low back pain and dis ability scores,the clinical successful rate was88.9%.The average percentage of the postoperative to preoperative disc height was128%.The slight displacement of PDN was observed in2patients,however there was no change of lumbar spinal mo bility.1patient had a bad recovery of back and leg pain.Conclusion PDN re placement can improve clinic symptoms,increase disc height and restore the normal lumbar motion as well.Its clinical effectiveness is excellent in short-term observation.
出处 《中华骨科杂志》 CAS CSCD 北大核心 2003年第6期353-357,共5页 Chinese Journal of Orthopaedics
关键词 治疗 人工髓核置换术 腰椎间盘突出症 术后 正常 腰痛 临床 病变 症状 生理 Lumbar vertebrae Intervertebral disk displacement Prosthesis implantation
  • 相关文献

参考文献9

  • 1Vaughan PA, Malcolm BW, Maistrelli GL. Results of L4-5 disc excision alone versus disc excision and fusion. Spine, 1988, 13: 690-695.
  • 2Lee CK. Accelerated degeneration of the segment adjacent to a lumbar fusion. Spine, 1988, 13: 375-377.
  • 3金大地,瞿东滨,赵亮,陈建庭,江建明.腰椎间盘人工髓核假体置换术临床应用初步报告[J].中华骨科杂志,2003,23(5):283-286. 被引量:33
  • 4刘尚礼,黄东生,郑召民,李春海,马若凡,陈燕涛,沈慧勇,李卫平.人工腰椎间盘置换术的临床应用[J].中华骨科杂志,2002,22(8):451-454. 被引量:36
  • 5Green TR, Fisher J, Stone M, et al. Polyethylene particles of a ‘critical size' are necessary for the induction of cytokines by macrophages in vitro. Biomaterials, 1998, 19: 2297-2302.
  • 6Wilke HJ, Kavanagh S, Neller S, et al. Effect of a prosthetic disc nucleus on the mobility and disc height of the L4-5 intervertebral disc postnucleotomy. J Neurosurg, 2001, 95 (2 Suppl): 208-214.
  • 7Klara PM, Ray CD. Artifical nucleus replacement: clinical experience. Spine, 2002, 27: 1374-1377.
  • 8Fairbank JC, Pynsent PB. The oswestry disability index. Spine, 2000,25: 2940-2952.
  • 9郑光新,赵晓鸥,刘广林,张利峰.Oswestry功能障碍指数评定腰痛患者的可信性[J].中国脊柱脊髓杂志,2002,12(1):13-15. 被引量:571

二级参考文献29

  • 1李家顺,赵定麟,欧阳跃平,潘杏然.退变性腰椎不稳症的早期诊断初探[J].上海医学,1989,12(7):395-398. 被引量:3
  • 2韩德韬,张发惠.椎间盘椎间孔和椎管间生物力学相互关系的实验研究[J].中华外科杂志,1989,27(10):581-584. 被引量:24
  • 3阮狄克,沈根标,周勇,丁勇,孙宏慧,陆瓞骥,梁智仁,隋延仿.同种异体椎间盘移植的实验研究[J].中华骨科杂志,1996,16(8):511-515. 被引量:10
  • 4Hochschuler SH. Artificial discs. Proceedings of the 68th AAOS Annual Meeting, San Francisco, 2001. 261-262.
  • 5Diwan AD, Parvataneni HK, Khan SN, et al. Current concepts in intervertebral disc restoration. Orthop Clin North Am, 2000, 31:453-464.
  • 6Zeegers WS, Bohnen LM, Laaper M, et al. Artificial disc replacement with the modular type SB CharitéⅢ: 2-year results in 50prospectively studied patients. Eur Spine J, 1999, 8:210-217.
  • 7Lemaire JP, Skalli W, Lavaste F, et al. Intervertebral disc prosthesis, results and prospects for the year 2000. Clin Orthop, 1997,(337): 64-76.
  • 8Loupasis GA, Stamos K, Katonis PG, et al. Seven- to 20-year outcome of lumbar discectomy. Spine, 1999, 24:2313-2317.
  • 9Lehmann TR, Spratt KF, Tozzi JE, et al. Long-term follow-up of lower lumbar fusion patients. Spine, 1987, 12:97-104.
  • 10Lee CK. Accelerated degeneration of the segment adjacent to a lumbar fusion. Spine, 1988, 13:375-377.

共引文献634

同被引文献78

引证文献13

二级引证文献60

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部