摘要
大部分氧化还原酶的催化反应需要烟酰型辅酶NAD(P) + 和NAD(P)H作为氧化剂或还原剂参与 ,由于氧化还原酶应用广泛而辅酶价格昂贵 ,使得辅酶再生逐渐成为研究热点 .综述了近年来NAD(P) + 和NAD(P)H酶法再生、电化学法及光化学法再生的研究进展 。
Regeneration of NAD(P)(+) and NAD(P)H captures more and more attention in recent years due to the following considerations: most oxidoreductase-catalyzed reactions need NAD(P)(+) or NAD(P)H as oxidants or reductants, oxidoreductases are used extensively, and NAD(P)(+) and NAD(P)H are quite expensive. This article reviews recent progress in regeneration of NAD(P)(+) and NAD(P)H by enzymatic, electrochemical and photochemical methods. The application and development status of regeneration technology are also illustrated.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2004年第11期1366-1379,共14页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金 (No.2 0 1 760 39)
天津市自然科学基金应用基础研究重点项目 (No.0 3380 2 4 1 1 )
跨世纪优秀人才培养计划
教育部优秀青年教师资助计划资助项目