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甲状腺未分化癌预后因素探讨──附80例临床分析 被引量:1

Study of prognostic factors on anaplastic thyroid carcinoma Clinical analysis of 80 cases
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摘要 甲状腺未分化癌预后很差。大宗的临床资料不多见。回顾我院头颈外科1960~1990年期间收治的80例甲状腺未分化癌和低分化癌,从临床角度探讨了影响其预后的有关因素。结果表明,低分化或未分化癌有可能由分化较好的甲状腺癌转化,能及时得到诊断和治疗者预后较好。术后加外照射放疗,比单纯手术效果好,单纯放疗虽大部分病人有缓解,但对生存率影响不明显。5年生存率14%,平均生存时间2.7±1年。作者认为,早期诊断、争取手术根治,配合放疗,有希望改善甲状腺未分化癌的预后。 Abstract The undifferenciatd or low-differenciated carcinoma of the thyroid gland trcated at the Department of Head and Neck Surgery from 1960-1990 were reviewed. The factors relative to prognosis were discussed. Operative treatment combined with radiotherapy had a significantly better survival rate as compared with surgery or radiotherapy alone。5-year suvival rate in our series was 14%, with a median suvival time of 2.7±1year.We consider that carly diagnoses and radical surgery combined with radiotherapy help to improve the prognosis of undifferenciated thyroid carcinoma.
出处 《耳鼻咽喉(头颈外科)》 1994年第3期167-170,共4页 Chinese Arch Otolaryngology-Head Neck Surg
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  • 1Urciuoli P,Ghinassi S,Iavarone C,et al.Thyroid anaplastic tumor:our experience.ChirItal,2003,55(6):835-840.
  • 2De Crevoisier R,Baudin E,Bachelot A,et al.Combined treatment of anaplastic thyroidcarcinoma with surgery,chemotherapy,and hyperfractionated accelerated externalradiotherapy.Int J Radiat Oncol Biol Phys,2004,60 (4):1137-1143.
  • 3Kihara M,Miyauchi A,Yamauchi A.Prognostic factors of anaplastic thyroid carcinoma.SurgToday,2004,34 (5):394-398.
  • 4Voigt W,Kegel T,Weiss M,et al.Potential activity of paclitaxel,vinorelbine andgemcitabine in anaplastic thyroid carcinoma.J Cancer Res Clin Oncol,2005,131 (9):585-590.
  • 5Kebebew E,Greenspan FS,Clark OH,et al.Anaplastic thyroid carcinoma.Treatment outcomeand prognostic factors.Cancer,2005,103(7):1330-1335.

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