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宫颈癌Ⅰ,Ⅱ期的淋巴结转移及治疗与预后的关系——附45例临床病例分析 被引量:9

Lymph Node's Metastasis, Treament, and Progorosis of Stage Ⅰ, ⅡCervix Carcinoma (Clinical analyses of 45 cases attached)
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摘要 目的探讨宫颈癌Ⅰ,Ⅱ期的淋巴结转移及治疗与预后关系。方法回顾性分析45例淋巴结转移患者,全部行广泛性子宫切除和盆腔淋巴结清扫术,其中IB22例,ⅡA 5例,ⅡB期18例,术前放疗32例,术后放疗31例,1个淋巴结转移25例,2个或2个以上淋巴结转移20例。结果淋巴结转移率12.30%(45/366),45例患者五年生存率68.89%。转移淋巴结<1.5 cm者,5年生存率84.62%,转移淋巴结≥1.5 cm者,5年生存率47.36%;1个淋巴结转移者5年生存率84.00%,2个或2个以上淋巴结转移者5年生存率50.00%。结论淋巴结状态可作为估计预后指标,术前术后放疗有助于降低局部复发率及远处转移率。 Objective: To explore the relationship between lymph node's metastasis and the treatment and prognosis in cervical cancer cases of stageⅠ, Ⅱ. Methods: We analysed 45 cases with lymph node metastasis, who had been performed extensive hysterectomy and pelvic-lymph-lymph node exenteration. Among whom, 22 cases are IB, 5ⅡA, 18ⅡB. Before the operation, 32 cases had been done radiation. After operation, 31 cases were given radiotherapy. Mearwhile, 25 cases have metastasis of one lymph node, and 20 have two or more than two metastases of lymph nodes. Results: The rate of lymph node metastasis was 12.3%; 5-year-overall survival rate of the 45 cases was 68.89%, and the survival rate of those whose metastases lymph nodes larger than 1.5 cm was 47.36% and the survival rate of those whose metastases lymph nodes small than 1.5cm was 84.62%. 5-year-overall survival rates of patients with one lymph node metastasis and two or more than two lymph node metastases were respectively 84.00% and 50.00%. Conclusions: The status of lymph nodes of patients can be used as evaluation of prognosis. And radiotherapy before and after the operation may help the patients low down the rate of the local recurrence and distant metastases.
作者 朱珠 陈志明
机构地区 湖南省肿瘤医院
出处 《中国现代医学杂志》 CAS CSCD 2004年第23期137-138,141,共3页 China Journal of Modern Medicine
关键词 宫颈癌 淋巴结转移 治疗 预后 cervical cancer Lymph node metastases treatment prognosis
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  • 1Tsai CS, Chyong HL, Chun CW, et aL The prognostic factors for patients with early cervical cancer treated by radical hysterectomy and post operative radioherapy[J]. Gynecol Oncol, 1999, 75(3):328-333.
  • 2Bradley JM, Dong SC, Joan LW, et al. Extent of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of stage Ⅰb and Ⅱ a cervical Carcinoma [J]. Oynecol Oncol, 1994, 54(1
  • 3Coelho FR, Franco EL, Kowalski LP, et al. Preoperative irradiation therapy and radical hysterectomy: prognostic value of tumor regression after initial irradiation of squamous cell carcinoma of the cervix[J]. Rev Paul Med, 1998, 116(3): 1700.
  • 4James F, Barter MD, Seng Jaw Soong, et al. Complications of combined radical hysterectomy-postoperative radiation therapy in women with early stage cervical Cancer [J]. Gynecologic Oncology, 1989, 32(2): 292.

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