摘要
目的探讨可溶性转铁蛋白受体(sTfR)、血清中铁蛋白(SF)及它们的比值 (sTfR/SF)在鉴别诊断难治性贫血(RA)与慢性再生障碍性贫血(CAA)中的意义。方法分别对34例难治性贫血与37例慢性再生障碍性贫血和30例正常对照组应用免疫比浊法和化学发光法测定sTfR和SF并计算其比值。结果正常人、RA和CAA患者三组之间SF有显著性差异 (P<0.05) ,sTfR有显著性差异(P<0.05)。sTfR/SF:三组间及两两比较均有极显著的差异(P<0.001) ,CAA>正常人>RA。结论同时测定血清SF、sTfR尤其是计算sTfR/SF值在RA与CAA的诊断和鉴别诊断中可提供重要的实验依据。
Objective To study the significance of serum ferritin,serum ferritin transferrin receptor、serum ferritin transferrin receptor/serum ferritin in the diagnosis of anemia as RA and CAA.Methods Immunity nephˉelomethy method and chemilumine_scence method were used to detect the targets of ferrin and transferrin receptor in three different groups,which were thirty_four in RA group,thirty_seven in CAA group and thirty in normal control group.Results The level of sTfR(3.16±1.71mg/L)in RA group was significantly higher than that in CAA group(1.30±0.43mg/L)and controls group(2.25±0.51mg/L).The level of SF in controls group and RA group is77.5±22.5μg/L,43.00±18.13μg/L respectively,which are significantly lower than those in RA group(601.75±370.57μg/L).Conclusions sTfR is a newsensitive target in the diagnosis of Iron Deficiency Anemia(IDA).SF is a helpful target in the diagnosis of IDA.It has important significance to detect sTfR and SF at the same time,especially to caculate sTfR/SF for diagnosing of anemia as RA and CAA.
出处
《中国微循环》
2004年第6期384-385,共2页
Journal of Chinese Microcirculation
