摘要
本文报道经免疫组化证实的8例B细胞性胸腺粘膜相关淋巴瘤,其特征为胸腺组织结构被中心细胞样小淋巴细胞浸润,但Hassall's小体仍可部分保存,并常形成含有分泌物的微囊,组成典型的淋巴上皮样病变,符合粘膜相关淋巴组织淋巴瘤的特征。免疫组化反应显示多数为MB2单抗反应阳性、λ或κ阳性的B细胞,属低度恶性淋巴瘤,对该瘤的组织发生,细胞成份,诊断和鉴别诊断进行了讨论,并指出应从胸腺瘤淋巴细胞型中单独分出来。
Ten cases of MALT-lymphoma of the thymus are reported in this article. Immunohistoche- mical studies showed eight of them to be B-cell MALT-lymphomas, with MB_2+ in 7 cases, IgG^+ in 5, λ^+ in 5 and K^+ in 3 cases. The remaining two cases showed no positive results. Histopa- thologically, all the ten cases had the features of thymic MALT-ML, with CCL cells infiltra- ting into Hassall's corpuscles and lymphoepithelial lesions. The histogenesis of T-MALT-ML has been discussed according to the embryogenesis of thymus and comparison with MALT-ML on other sites.
出处
《实用肿瘤杂志》
CAS
北大核心
1993年第1期21-24,共4页
Journal of Practical Oncology
关键词
胸腺
淋巴瘤
免疫组织化学
thymus MALT-lymphoma immunohistochemistry
