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植入自体雪旺氏细胞的胎儿神经移植修复周围神经缺损的临床研究

CLINICAL STUDY TO BRIDGE PERIPHERAL NERVE DEFECT WITH FETAL NERVE IMPIANTED ACCEPTOR'S SC
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摘要 目的:探讨修复周围神经缺损新的手术方法和验证胎儿神经、雪旺氏细胞对神经再生的作用。方法:临床应用胎儿神经加自体雪旺氏细胞修复周围神经缺损32例(45条),术后1年进行神经功能评定,随访1-3年。结果:32例(45条)周围神经损伤,按Seddon的周围神经损伤术后恢复评定标准进行评定,优良率为65.8%。结论:植入自体雪旺氏细胞的胎儿神经移植是一种修复周围神经缺损的新方法,具有进一步深入研究价值。 Objective: To investigate the novel methods to graft peripheral nerve defect and determined the effect of fetal nerve and SC on promoting nerve regeneration. Methods: 32 patients (include 45 nerve stumps) were bridged with fetal nerve implanted acceptor's SC clinically. Functional assessment after operation one year and follow investigation during one to three years were accomplished. Results:According to Seddon's method of estimate function of repairing peripheral nerve, excellence and favorable function comeback ratio reached to the 65.8%. Conclusion: The fetal nerve implanted acceptor's SC is a novel graft to bridge the defect of peripheral nerve and should be more research clinically.
出处 《海南医学院学报》 CAS 2004年第6期369-372,共4页 Journal of Hainan Medical University
关键词 周围神经缺损 雪旺氏细胞 自体 胎儿 植入 神经移植 修复 结论 研究价值 目的 Fetal nerve, Schwann cells, Peripheral nerve repair
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