摘要
目的:探索皮质下缺血性脑血管病MRI表现与血管性痴呆之间的关系。方法:对比分析了皮质下多发梗死28例痴呆患者和33例非痴呆患者的MRI表现,采用Logistic回归分析皮质下缺血性血管性痴呆的影像学相关高危因素。结果:痴呆组中顶叶皮质下、内囊膝部和丘脑的梗死发生率,顶叶皮质下、侧脑室体旁前部、内囊膝部和丘脑平均梗死数目,4级LA的出现率以及所有脑萎缩指标均明显大于对照组(P<0.05)。但Logistic回归后,只有平均脑沟宽度、侧脑室指数和丘脑梗死的数目进入了方程。结论:皮质下缺血性血管性痴呆可能与脑萎缩的程度和丘脑梗死的数目密切相关。
Objective: To explore the correlation of MRI of subcortical ischemic vascular disease and vascular dementia. Methods: The MRI features were analysed and compared between 28 cases of dementia and 33 cases of nondementia with subcortical multi-infarct. Logistic regression analyses were used to identify MRI risk factors of subcortical ischemic vascular dementia. Results: The frequency of parietal subcortical, genu internal capusle and thalamus infarcts were more frequent in dementia group than in control group(P<0. 05). The number of parietal subcortical, anterior white matter a-round the body of lateral ventricle, genu internal capusle, and thalamus infarcts were more in dementia group than in control group(P<0. 05). Leukoaraiosis of 4 degree was more common in dementia group than in control group(P<0. 05). The mean width of the cerebral sulci and sylvian fissure, the width of third ventricle, the frontal horn index, the lateral ventricle index and Huchman index in dementia group were larger than in control group significantly(P<0. 05). Logistic regression showed that the mean width of the cerebral sulci(OR=2. 740, P = 0. 017), the lateral ventricle index (OR= 1. 767, P=0. 012)and the number of thalamus infarets(OR = 5. 807,P = 0. 036) were significantly correlated with vascular dementia. Conclusion: Subcortical ischemic vascular dementia may be correlated with the degree of brain atrophy and the number of thalamus infarcts.
出处
《脑与神经疾病杂志》
2005年第1期16-19,共4页
Journal of Brain and Nervous Diseases
关键词
皮质下缺血性脑血管病
血管性痴呆
磁共振成像
subcortical ischemic vascular disease vascular dementia magnetic resonance imaging
