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颅咽管瘤的显微手术治疗 被引量:7

Microsurgical resection of craniopharyngiomas
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摘要 目的 探讨颅咽管瘤显微手术治疗的方法和入路。方法 回顾性分析 32例颅咽管瘤显微手术的方法、并发症和治疗结果 ,总结临床处置过程中的体会。结果  31例患者经翼点入路、1例经前胼胝体入路完成手术。经术中观察及术后CT和MRI复查证实 ,肿瘤全切除 2 6例 ,次全切除 3例 ,部分切除 2例。术后出现尿崩症 2 4例 ,高钠高氯血症 18例 ,低钠血症 5例 ,高热 11例。临床痊愈出院 12例 ,好转出院 19例 ,死亡 1例。结论 采用显微手术全切颅咽管瘤 ,效果良好 ;术前即有明显下丘脑功能损害者 ,手术风险较大 ,预后差 ;鞍区颅咽管瘤采用翼点入路是最佳选择。 Objective To investigate the method and approach of microsurgical resection of craniopharyngiomas .Methods The clinical data of 32 cases among the patients with craniopharyngiomas, who were hospitalized in our department from January, 1998 to June, 2004, were analyzed retrospectively.Results The operation was performed via a pterional approach in 31 cases and a transcallosal approach in 1 case. The tumor removal was considered total in 26 cases, subtotal in 3 cases, and partial in 2 cases. Twenty four cases were suffered from diabetes insipidus,18 cases from hypernatremia and hyperchloraemia, 5 cases from hyponatremia , and 11 cases from hyperpyrexia after operations. Twelve cases recovered clinically, 19 cases improved , and 1 case died. Conclusion The total removal of craniopharyngiomas may achieve good curative effect with microsurgical technique . The prognosis is poor and the operation risk is great if there is functional lesion of hypothalamus preoperation. Employing pterional approach may be the optimal way for total removal of craniopharyngiomas in sallar area.
出处 《中华神经外科疾病研究杂志》 CAS 2004年第6期507-510,共4页 Chinese Journal of Neurosurgical Disease Research
关键词 颅咽管瘤 显微手术 手术入路 Craniopharyngioma Microsurgery Operative approach
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