摘要
许多大型海藻含有具潜在重要药用价值的次生代谢物质,通常这些物质在藻体中含量极微,大型海藻体本身也不像微藻那样易在短期内大量获取,并且这些物质化学结构复杂,这使得直接提取或者人工合成极为困难。利用光生物反应器培养大型海藻细胞或组织,可以经济、无限量和资源循环再利用的方式,在植物体外合成生产重要的海洋植物次生代谢物质。光生物反应器所提供的可调控和工程优化的培养环境有望成为优化次生代谢物生物合成的有效手段。光生物反应器培养大型海藻细胞或组织也是大型海藻养殖业育苗技术发展的一个重要方向。综述了近10年来光生物反应器培养大型海藻细胞或组织在培养条件以及生长动力学模型方面国内外的研究进展,并对该领域未来可能的研究方向作一展望。
Macroalgae are a rich and diverse source of important secondary metabolites with pharmaceutical potentials. The extremely low content in the algae, the difficulty of obtaining algal biomass on an unlimited scale, and the complicated molecular structure of these metabolic compounds, however, discourage the direct extraction and chemical synthesis. Photolithotrophic cultivation of macroalgal cells or tissues in photobioreactors under controlled conditions provides economical, unlimited and renewable resources to obtain biomass and metabolites. It is an effective way to optimize culture conditions, especially those that specifically important in the stimulation of secondary metabolic biosynthesis, and to achieve the future commercial productions of the relevant biochemicals. Furthermore, photobioreactor cultivation of macroalgal cells or tissues leads to and important application in the breeding techniques of economic-scale aquacultures of macroalgae. The progress in this field during the last decade with focus on bioreactor cultivation parameters and growth kinetic models, and the future development were summarized.
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2005年第1期18-24,共7页
China Biotechnology
基金
国家"863"计划资助项目(2002AA629070)
