摘要
目的通过大黄不同炮制品的水煎液和甲醇提取液中结合蒽醌类化合物的含量比较研究,探索酒炙大黄泻下力缓与结合蒽醌含量的关系。方法采用分光光度法分别测定不同炮制品水煎液、甲醇提取液中游离蒽醌、结合蒽醌的含量。结果水煎液中,游离蒽醌生品与炮制品相差不大,但是结合蒽醌酒炙品比生品高的多;而甲醇提取液中,生品的游离蒽醌、结合蒽醌均较酒炙品高。结论临床汤方,多为水煎,用结合蒽醌含量减少来解释酒炙大黄缓泻作用可能并不完全,酒炙大黄缓泻的真正原因可能需要从多个层次上进行探讨。
AIM: To explore the relationship of the decrease of the catharticizing action and the conjugated anthraquinone after Radix et Rhizoma Rhei was in the process of stirred-fry-with wine by comparing the content of conjugated anthraquinone among different processing Radix et Rhizoma Rhei in the solution decocted by water and extrected by methanol. METHODS: The spectrophotometer was used to assay the content of free anthraquinone and conjugated anthraquinone of different proccssing Rudix et Rhizoma Rhei in the solution decocted by water and extracted by methanol. RESULTS: In the solution decocted by water there was little difference in free anthraquinone between the raw and the processing products, however, the conjugated anthraquinone of the precessing product was much higher than the raw. CONCLUSION: The decrease of the conjugated anthraquinone can’t fully account for the reduction of the catharticizing action of Radix et Rhizoma Rhei in the process of stirred-fry with wine. The real cause needs to be explored in many aspects.
出处
《中成药》
CAS
CSCD
北大核心
2005年第1期49-51,共3页
Chinese Traditional Patent Medicine
关键词
大黄
不同炮制品
蒽醌类化合物
泻下理论
Radix et Rhizoma Rhei
different processed Radix et Rhizoma Rhei
the anthraquinone
the theory of catharticizing
