摘要
目的总结腹部多器官联合移植的围手术期处理经验。方法我院自2001年10月至2005年1月共施行19例腹部多器官联合移植术,其中胰肾联合移植6例、肝肾联合移植12例、肝胰联合移植1例;分析手术方法、免疫抑制剂的使用和术后并发症处理的方法。结果19例患者手术均获成功,术后发生FK506中毒1例(5.3%),发生急性排斥反应3例(15.8%),消化道出血发生2例(10.5%),腹腔出血1例(5.3%),肺部感染1例(5.3%),经相应治疗后好转。结论腹部多器官联合移植成功的关键是作好供体选择、保证供器官质量、选择适当手术方式、术后合理应用免疫抑制剂以及有效防治术后并发症。
Objective To summarize the experience with perioperative management of multiorgan transplantation. Methods From October 2001 to January 2005, 19 patients received multiorgan transplantation in Nanfang Hospital, including 6 with simultaneous kidney-pancreas transplantation (SKPT), 12 with combined liver-kidney transplantation (CLKT), and 1 with simultaneous liver-pancreas transplantation (SLPT). The surgical techniques, application of immunosuppressants, and complication management were reviewed. Results All transplantation procedures were performed successfully. The transplantation-related complications included tacrolimus-induced renal toxicosis in 1 (5.3%) case, acute graft rejection in 3 (15.8%) cases, intestinal hemorrhage in 2 (10.5%) cases, intra-abdominal hemorrhage in 1 (5.3%) case, and lung infection in 1 (5.3%) case, all of which were cured after proper treatment. Conclusions Donor selection, good quality of the donor organ, proper surgical approaches, adequate use of the-mmunosuppressants, and prevention of complications are essential to the success of multiorgan transplantation.
出处
《第一军医大学学报》
CSCD
北大核心
2005年第2期165-167,共3页
Journal of First Military Medical University
基金
全军医学科学技术研究"十五"计划基金重点课题项目(01Z049)
广东省科技攻关项目(2KM05101S)
关键词
联合移植
围手术期
肝脏移植
肾脏移植
胰腺移植
combined transplantation
perioperative management
liver transplantation
kidney transplantation
pancreas transplantation
