摘要
目的 总结肺泡蛋白沉积症 (pulmonaryalveolarproteinosis,PAP)的临床特征、诊断及治疗。 方法 收集 2 0 0 3年～ 2 0 0 4年南京市鼓楼医院呼吸内科经病理学确诊为PAP患者 3例。结果 PAP的临床症状及体征缺乏特异性 ,胸部CT可见“地图样”改变或“铺路石”征 ,肺活检及支气管肺泡灌洗液过碘酸雪夫PAS染色阳性 ,可用于诊断。结论 由于本病罕见 ,易误诊误治 ,应加强对本病的认识 ,全肺灌洗疗效肯定。
ObjectiveTo summarize and analyze the clinical manifestations of pulmonary alveolar proteinosis (PAP) and its treatment.Methods The data was collected from Drum Tower Hospital of Nanjing from 2003 to 2004 and three cases of PAP patients were confirmed by means of pathological diagnosis.Results There were lack of the clinical symptoms and physical signs of PAP,but topical chest CT scan showed 'map-like' or 'cobble stone-like' changes.The cases were finally confirmed by lung biopsy and examination of bronchoalveolar lavage fluid with periodic acid-schiff (PAS) staining.Conclusion PAP is rarely seen in clinic and its symptom can easily result in misdiagnosis.Therefore,it is essential to be highly conscious about the demonstration of the disease.Whole lung lavage can be an efficient diagnosis and therapy for PAP.
出处
《皖南医学院学报》
CAS
2005年第1期52-54,共3页
Journal of Wannan Medical College
